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BIN1 is a key regulator of proinflammatory and neurodegeneration-related activation in microglia.
Sudwarts A, Ramesha S, Gao T, Ponnusamy M, Wang S, Hansen M, Kozlova A, Bitarafan S, Kumar P, Beaulieu-Abdelahad D, Zhang X, Collier L, Szekeres C, Wood LB, Duan J, Thinakaran G, Rangaraju S. Sudwarts A, et al. Among authors: duan j. Mol Neurodegener. 2022 May 7;17(1):33. doi: 10.1186/s13024-022-00535-x. Mol Neurodegener. 2022. PMID: 35526014 Free PMC article.
Loss of function of OTUD7A in the schizophrenia- associated 15q13.3 deletion impairs synapse development and function in human neurons.
Kozlova A, Zhang S, Kotlar AV, Jamison B, Zhang H, Shi S, Forrest MP, McDaid J, Cutler DJ, Epstein MP, Zwick ME, Pang ZP, Sanders AR, Warren ST, Gejman PV, Mulle JG, Duan J. Kozlova A, et al. Among authors: duan j. Am J Hum Genet. 2022 Aug 4;109(8):1500-1519. doi: 10.1016/j.ajhg.2022.07.001. Am J Hum Genet. 2022. PMID: 35931052 Free PMC article.
Multiple genes in a single GWAS risk locus synergistically mediate aberrant synaptic development and function in human neurons.
Zhang S, Zhang H, Forrest MP, Zhou Y, Sun X, Bagchi VA, Kozlova A, Santos MD, Piguel NH, Dionisio LE, Sanders AR, Pang ZP, He X, Penzes P, Duan J. Zhang S, et al. Among authors: duan j. Cell Genom. 2023 Aug 28;3(9):100399. doi: 10.1016/j.xgen.2023.100399. eCollection 2023 Sep 13. Cell Genom. 2023. PMID: 37719141 Free PMC article.
Alzheimer's disease risk allele of PICALM causes detrimental lipid droplets in microglia.
Kozlova A, Zhang S, Sudwarts A, Zhang H, Smirnou S, Sun X, Stephenson K, Zhao X, Jamison B, Ponnusamy M, He X, Pang ZP, Sanders AR, Bellen HJ, Thinakaran G, Duan J. Kozlova A, et al. Among authors: duan j. Res Sq [Preprint]. 2024 May 24:rs.3.rs-4407146. doi: 10.21203/rs.3.rs-4407146/v1. Res Sq. 2024. PMID: 38826437 Free PMC article. Preprint.
Allele-specific open chromatin in human iPSC neurons elucidates functional disease variants.
Zhang S, Zhang H, Zhou Y, Qiao M, Zhao S, Kozlova A, Shi J, Sanders AR, Wang G, Luo K, Sengupta S, West S, Qian S, Streit M, Avramopoulos D, Cowan CA, Chen M, Pang ZP, Gejman PV, He X, Duan J. Zhang S, et al. Among authors: duan j. Science. 2020 Jul 31;369(6503):561-565. doi: 10.1126/science.aay3983. Science. 2020. PMID: 32732423 Free PMC article.
Transcriptome study of differential expression in schizophrenia.
Sanders AR, Göring HH, Duan J, Drigalenko EI, Moy W, Freda J, He D, Shi J; MGS; Gejman PV. Sanders AR, et al. Among authors: duan j. Hum Mol Genet. 2013 Dec 15;22(24):5001-14. doi: 10.1093/hmg/ddt350. Epub 2013 Jul 30. Hum Mol Genet. 2013. PMID: 23904455 Free PMC article.
6,516 results