Hofmanova T - Search Results

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Halogenated monopyridinium oximes are less effective in reactivation of phosphylated cholinesterases than bisquaternary oximes.

Kohoutova Z, Prchalova E, Andrys R, Knittelova K, Formanova M, Hofmanova T, Psotka M, Musilek K, Derat E, Malinak D. Kohoutova Z, et al. Among authors: hofmanova t. Bioorg Chem. 2024 Dec;153:107904. doi: 10.1016/j.bioorg.2024.107904. Epub 2024 Oct 22. Bioorg Chem. 2024. PMID: 39467508

Brominated oxime nucleophiles are efficiently reactivating cholinesterases inhibited by nerve agents.

Prchalova E, Andrys R, Pejchal J, Kohoutova Z, Knittelova K, Hofmanova T, Skarka A, Dlabkova A, Psotka M, Prchal L, Musilek K, Karasova JZ, Malinak D. Prchalova E, et al. Among authors: hofmanova t. Arch Toxicol. 2024 Sep;98(9):2937-2952. doi: 10.1007/s00204-024-03791-6. Epub 2024 May 24. Arch Toxicol. 2024. PMID: 38789714

Halogen substituents enhance oxime nucleophilicity for reactivation of cholinesterases inhibited by nerve agents.

Zorbaz T, Malinak D, Hofmanova T, Maraković N, Žunec S, Hrvat NM, Andrys R, Psotka M, Zandona A, Svobodova J, Prchal L, Fingler S, Katalinić M, Kovarik Z, Musilek K. Zorbaz T, et al. Among authors: hofmanova t. Eur J Med Chem. 2022 Aug 5;238:114377. doi: 10.1016/j.ejmech.2022.114377. Epub 2022 Apr 27. Eur J Med Chem. 2022. PMID: 35526478

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