Simon JM - Search Results

1

Rescue of behavioral and electrophysiological phenotypes in a Pitt-Hopkins syndrome mouse model by genetic restoration of Tcf4 expression.

Kim H, Gao EB, Draper A, Berens NC, Vihma H, Zhang X, Higashi-Howard A, Ritola KD, Simon JM, Kennedy AJ, Philpot BD. Kim H, et al. Among authors: simon jm. Elife. 2022 May 10;11:e72290. doi: 10.7554/eLife.72290. Elife. 2022. PMID: 35535852 Free PMC article.

2

Gene length matters in neurons.

Zylka MJ, Simon JM, Philpot BD. Zylka MJ, et al. Among authors: simon jm. Neuron. 2015 Apr 22;86(2):353-5. doi: 10.1016/j.neuron.2015.03.059. Neuron. 2015. PMID: 25905808 Free PMC article.

3

Topoisomerase 1 Regulates Gene Expression in Neurons through Cleavage Complex-Dependent and -Independent Mechanisms.

Mabb AM, Simon JM, King IF, Lee HM, An LK, Philpot BD, Zylka MJ. Mabb AM, et al. Among authors: simon jm. PLoS One. 2016 May 27;11(5):e0156439. doi: 10.1371/journal.pone.0156439. eCollection 2016. PLoS One. 2016. PMID: 27231886 Free PMC article.

4

Enhanced Nociception in Angelman Syndrome Model Mice.

McCoy ES, Taylor-Blake B, Aita M, Simon JM, Philpot BD, Zylka MJ. McCoy ES, et al. Among authors: simon jm. J Neurosci. 2017 Oct 18;37(42):10230-10239. doi: 10.1523/JNEUROSCI.1018-17.2017. Epub 2017 Sep 20. J Neurosci. 2017. PMID: 28931574 Free PMC article.

5

Phan BN, Bohlen JF, Davis BA, Ye Z, Chen HY, Mayfield B, Sripathy SR, Cerceo Page S, Campbell MN, Smith HL, Gallop D, Kim H, Thaxton CL, Simon JM, Burke EE, Shin JH, Kennedy AJ, Sweatt JD, Philpot BD, Jaffe AE, Maher BJ. Phan BN, et al. Among authors: simon jm. Nat Neurosci. 2020 Mar;23(3):375-385. doi: 10.1038/s41593-019-0578-x. Epub 2020 Feb 3. Nat Neurosci. 2020. PMID: 32015540 Free PMC article.

6

A small-molecule screen reveals novel modulators of MeCP2 and X-chromosome inactivation maintenance.

Lee HM, Kuijer MB, Ruiz Blanes N, Clark EP, Aita M, Galiano Arjona L, Kokot A, Sciaky N, Simon JM, Bhatnagar S, Philpot BD, Cerase A. Lee HM, et al. Among authors: simon jm. J Neurodev Disord. 2020 Nov 10;12(1):29. doi: 10.1186/s11689-020-09332-3. J Neurodev Disord. 2020. PMID: 33172406 Free PMC article.

7

Dual-isoform hUBE3A gene transfer improves behavioral and seizure outcomes in Angelman syndrome model mice.

Judson MC, Shyng C, Simon JM, Davis CR, Punt AM, Salmon MT, Miller NW, Ritola KD, Elgersma Y, Amaral DG, Gray SJ, Philpot BD. Judson MC, et al. Among authors: simon jm. JCI Insight. 2021 Oct 22;6(20):e144712. doi: 10.1172/jci.insight.144712. JCI Insight. 2021. PMID: 34676830 Free PMC article.

8

ZHX2 promotes HIF1α oncogenic signaling in triple-negative breast cancer.

Fang W, Liao C, Shi R, Simon JM, Ptacek TS, Zurlo G, Ye Y, Han L, Fan C, Bao L, Ortiz CL, Lin HR, Manocha U, Luo W, Peng Y, Kim WY, Yang LW, Zhang Q. Fang W, et al. Among authors: simon jm. Elife. 2021 Nov 15;10:e70412. doi: 10.7554/eLife.70412. Elife. 2021. PMID: 34779768 Free PMC article.

9

RNA-binding deficient TDP-43 drives cognitive decline in a mouse model of TDP-43 proteinopathy.

Necarsulmer JC, Simon JM, Evangelista BA, Chen Y, Tian X, Nafees S, Marquez AB, Jiang H, Wang P, Ajit D, Nikolova VD, Harper KM, Ezzell JA, Lin FC, Beltran AS, Moy SS, Cohen TJ. Necarsulmer JC, et al. Among authors: simon jm. Elife. 2023 Oct 11;12:RP85921. doi: 10.7554/eLife.85921. Elife. 2023. PMID: 37819053 Free PMC article.

10

Heterogeneity in the progression of retinal pathologies in mice harboring patient mimicking Impg2 mutations.

Williams BN, Draper A, Lang PF, Lewis TR, Smith AL, Mayerl SJ, Rougié M, Simon JM, Arshavsky VY, Greenwald SH, Gamm DM, Pinilla I, Philpot BD. Williams BN, et al. Among authors: simon jm. Hum Mol Genet. 2024 Feb 18;33(5):448-464. doi: 10.1093/hmg/ddad199. Hum Mol Genet. 2024. PMID: 37975905 Free PMC article.

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