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LY-CoV1404 (bebtelovimab) potently neutralizes SARS-CoV-2 variants.
Westendorf K, Žentelis S, Wang L, Foster D, Vaillancourt P, Wiggin M, Lovett E, van der Lee R, Hendle J, Pustilnik A, Sauder JM, Kraft L, Hwang Y, Siegel RW, Chen J, Heinz BA, Higgs RE, Kallewaard NL, Jepson K, Goya R, Smith MA, Collins DW, Pellacani D, Xiang P, de Puyraimond V, Ricicova M, Devorkin L, Pritchard C, O'Neill A, Dalal K, Panwar P, Dhupar H, Garces FA, Cohen CA, Dye JM, Huie KE, Badger CV, Kobasa D, Audet J, Freitas JJ, Hassanali S, Hughes I, Munoz L, Palma HC, Ramamurthy B, Cross RW, Geisbert TW, Menachery V, Lokugamage K, Borisevich V, Lanz I, Anderson L, Sipahimalani P, Corbett KS, Yang ES, Zhang Y, Shi W, Zhou T, Choe M, Misasi J, Kwong PD, Sullivan NJ, Graham BS, Fernandez TL, Hansen CL, Falconer E, Mascola JR, Jones BE, Barnhart BC. Westendorf K, et al. Among authors: lokugamage k. Cell Rep. 2022 May 17;39(7):110812. doi: 10.1016/j.celrep.2022.110812. Epub 2022 Apr 25. Cell Rep. 2022. PMID: 35568025 Free PMC article.
An Infectious cDNA Clone of SARS-CoV-2.
Xie X, Muruato A, Lokugamage KG, Narayanan K, Zhang X, Zou J, Liu J, Schindewolf C, Bopp NE, Aguilar PV, Plante KS, Weaver SC, Makino S, LeDuc JW, Menachery VD, Shi PY. Xie X, et al. Among authors: lokugamage kg. Cell Host Microbe. 2020 May 13;27(5):841-848.e3. doi: 10.1016/j.chom.2020.04.004. Epub 2020 Apr 13. Cell Host Microbe. 2020. PMID: 32289263 Free PMC article.
Spike mutation D614G alters SARS-CoV-2 fitness and neutralization susceptibility.
Plante JA, Liu Y, Liu J, Xia H, Johnson BA, Lokugamage KG, Zhang X, Muruato AE, Zou J, Fontes-Garfias CR, Mirchandani D, Scharton D, Bilello JP, Ku Z, An Z, Kalveram B, Freiberg AN, Menachery VD, Xie X, Plante KS, Weaver SC, Shi PY. Plante JA, et al. bioRxiv [Preprint]. 2020 Sep 2:2020.09.01.278689. doi: 10.1101/2020.09.01.278689. bioRxiv. 2020. Update in: Nature. 2021 Apr;592(7852):116-121. doi: 10.1038/s41586-020-2895-3 PMID: 32908978 Free PMC article. Updated. Preprint.
Spike mutation D614G alters SARS-CoV-2 fitness and neutralization susceptibility.
Shi PY, Plante J, Liu Y, Liu J, Xia H, Johnson B, Lokugamage K, Zhang X, Muruato A, Zou J, Fontes-Garfias C, Mirchandani D, Scharton D, Kalveram B, Bilello J, Ku Z, An Z, Freiberg A, Menachery V, Xie X, Plante K, Weaver S. Shi PY, et al. Among authors: lokugamage k. Res Sq [Preprint]. 2020 Sep 10:rs.3.rs-70482. doi: 10.21203/rs.3.rs-70482/v1. Res Sq. 2020. Update in: Nature. 2021 Apr;592(7852):116-121. doi: 10.1038/s41586-020-2895-3 PMID: 32935091 Free PMC article. Updated. Preprint.
Type I Interferon Susceptibility Distinguishes SARS-CoV-2 from SARS-CoV.
Lokugamage KG, Hage A, de Vries M, Valero-Jimenez AM, Schindewolf C, Dittmann M, Rajsbaum R, Menachery VD. Lokugamage KG, et al. J Virol. 2020 Nov 9;94(23):e01410-20. doi: 10.1128/JVI.01410-20. Print 2020 Nov 9. J Virol. 2020. PMID: 32938761 Free PMC article.
Spike mutation D614G alters SARS-CoV-2 fitness.
Plante JA, Liu Y, Liu J, Xia H, Johnson BA, Lokugamage KG, Zhang X, Muruato AE, Zou J, Fontes-Garfias CR, Mirchandani D, Scharton D, Bilello JP, Ku Z, An Z, Kalveram B, Freiberg AN, Menachery VD, Xie X, Plante KS, Weaver SC, Shi PY. Plante JA, et al. Nature. 2021 Apr;592(7852):116-121. doi: 10.1038/s41586-020-2895-3. Epub 2020 Oct 26. Nature. 2021. PMID: 33106671 Free PMC article.
Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis.
Johnson BA, Xie X, Bailey AL, Kalveram B, Lokugamage KG, Muruato A, Zou J, Zhang X, Juelich T, Smith JK, Zhang L, Bopp N, Schindewolf C, Vu M, Vanderheiden A, Winkler ES, Swetnam D, Plante JA, Aguilar P, Plante KS, Popov V, Lee B, Weaver SC, Suthar MS, Routh AL, Ren P, Ku Z, An Z, Debbink K, Diamond MS, Shi PY, Freiberg AN, Menachery VD. Johnson BA, et al. Among authors: lokugamage kg. Nature. 2021 Mar;591(7849):293-299. doi: 10.1038/s41586-021-03237-4. Epub 2021 Jan 25. Nature. 2021. PMID: 33494095 Free PMC article.
Engineering SARS-CoV-2 using a reverse genetic system.
Xie X, Lokugamage KG, Zhang X, Vu MN, Muruato AE, Menachery VD, Shi PY. Xie X, et al. Nat Protoc. 2021 Mar;16(3):1761-1784. doi: 10.1038/s41596-021-00491-8. Epub 2021 Jan 29. Nat Protoc. 2021. PMID: 33514944 Free PMC article. Review.
55 results