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Page 1
Cross-Packaging and Capsid Mosaic Formation in Multiplexed AAV Libraries.
Schmit PF, Pacouret S, Zinn E, Telford E, Nicolaou F, Broucque F, Andres-Mateos E, Xiao R, Penaud-Budloo M, Bouzelha M, Jaulin N, Adjali O, Ayuso E, Vandenberghe LH. Schmit PF, et al. Among authors: pacouret s. Mol Ther Methods Clin Dev. 2019 Nov 26;17:107-121. doi: 10.1016/j.omtm.2019.11.014. eCollection 2020 Jun 12. Mol Ther Methods Clin Dev. 2019. PMID: 31909084 Free PMC article.
Chemical modification of the adeno-associated virus capsid to improve gene delivery.
Mével M, Bouzelha M, Leray A, Pacouret S, Guilbaud M, Penaud-Budloo M, Alvarez-Dorta D, Dubreil L, Gouin SG, Combal JP, Hommel M, Gonzalez-Aseguinolaza G, Blouin V, Moullier P, Adjali O, Deniaud D, Ayuso E. Mével M, et al. Among authors: pacouret s. Chem Sci. 2019 Dec 9;11(4):1122-1131. doi: 10.1039/c9sc04189c. Chem Sci. 2019. PMID: 34084369 Free PMC article.
Characterization of residual microRNAs in AAV vector batches produced in HEK293 mammalian cells and Sf9 insect cells.
Penaud-Budloo M, Lecomte E, Lecomte Q, Pacouret S, Broucque F, Guy-Duché A, Dupont JB, Jeanson-Leh L, Robin C, Blouin V, Ayuso E, Adjali O. Penaud-Budloo M, et al. Among authors: pacouret s. Mol Ther Methods Clin Dev. 2024 Jul 25;32(3):101305. doi: 10.1016/j.omtm.2024.101305. eCollection 2024 Sep 12. Mol Ther Methods Clin Dev. 2024. PMID: 39220637 Free PMC article.
Systematic multi-trait AAV capsid engineering for efficient gene delivery.
Eid FE, Chen AT, Chan KY, Huang Q, Zheng Q, Tobey IG, Pacouret S, Brauer PP, Keyes C, Powell M, Johnston J, Zhao B, Lage K, Tarantal AF, Chan YA, Deverman BE. Eid FE, et al. Among authors: pacouret s. Nat Commun. 2024 Aug 4;15(1):6602. doi: 10.1038/s41467-024-50555-y. Nat Commun. 2024. PMID: 39097583 Free PMC article.
An AAV capsid reprogrammed to bind human transferrin receptor mediates brain-wide gene delivery.
Huang Q, Chan KY, Wu J, Botticello-Romero NR, Zheng Q, Lou S, Keyes C, Svanbergsson A, Johnston J, Mills A, Lin CY, Brauer PP, Clouse G, Pacouret S, Harvey JW, Beddow T, Hurley JK, Tobey IG, Powell M, Chen AT, Barry AJ, Eid FE, Chan YA, Deverman BE. Huang Q, et al. Among authors: pacouret s. Science. 2024 Jun 14;384(6701):1220-1227. doi: 10.1126/science.adm8386. Epub 2024 May 16. Science. 2024. PMID: 38753766
13 results