Granzier HL - Search Results

1

HDAC6 modulates myofibril stiffness and diastolic function of the heart.

Lin YH, Major JL, Liebner T, Hourani Z, Travers JG, Wennersten SA, Haefner KR, Cavasin MA, Wilson CE, Jeong MY, Han Y, Gotthardt M, Ferguson SK, Ambardekar AV, Lam MP, Choudhary C, Granzier HL, Woulfe KC, McKinsey TA. Lin YH, et al. Among authors: granzier hl. J Clin Invest. 2022 May 16;132(10):e148333. doi: 10.1172/JCI148333. J Clin Invest. 2022. PMID: 35575093 Free PMC article.

2

Adaptations in titin's spring elements in normal and cardiomyopathic hearts.

Granzier H, Labeit D, Wu Y, Witt C, Watanabe K, Lahmers S, Gotthardt M, Labeit S. Granzier H, et al. Adv Exp Med Biol. 2003;538:517-30; discussion 530-1. doi: 10.1007/978-1-4419-9029-7_46. Adv Exp Med Biol. 2003. PMID: 15098695

3

Targeted deletion of titin N2B region leads to diastolic dysfunction and cardiac atrophy.

Radke MH, Peng J, Wu Y, McNabb M, Nelson OL, Granzier H, Gotthardt M. Radke MH, et al. Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3444-9. doi: 10.1073/pnas.0608543104. Epub 2007 Feb 20. Proc Natl Acad Sci U S A. 2007. PMID: 17360664 Free PMC article.

4

Functional genomics of chicken, mouse, and human titin supports splice diversity as an important mechanism for regulating biomechanics of striated muscle.

Granzier H, Radke M, Royal J, Wu Y, Irving TC, Gotthardt M, Labeit S. Granzier H, et al. Am J Physiol Regul Integr Comp Physiol. 2007 Aug;293(2):R557-67. doi: 10.1152/ajpregu.00001.2007. Epub 2007 May 23. Am J Physiol Regul Integr Comp Physiol. 2007. PMID: 17522126 Free article.

5

Truncation of titin's elastic PEVK region leads to cardiomyopathy with diastolic dysfunction.

Granzier HL, Radke MH, Peng J, Westermann D, Nelson OL, Rost K, King NM, Yu Q, Tschöpe C, McNabb M, Larson DF, Labeit S, Gotthardt M. Granzier HL, et al. Circ Res. 2009 Sep 11;105(6):557-64. doi: 10.1161/CIRCRESAHA.109.200964. Epub 2009 Aug 13. Circ Res. 2009. PMID: 19679835 Free PMC article.

6

Altered contractility of skeletal muscle in mice deficient in titin's M-band region.

Ottenheijm CA, Hidalgo C, Rost K, Gotthardt M, Granzier H. Ottenheijm CA, et al. J Mol Biol. 2009 Oct 16;393(1):10-26. doi: 10.1016/j.jmb.2009.08.009. Epub 2009 Aug 13. J Mol Biol. 2009. PMID: 19683008 Free PMC article.

7

Excision of titin's cardiac PEVK spring element abolishes PKCalpha-induced increases in myocardial stiffness.

Hudson BD, Hidalgo CG, Gotthardt M, Granzier HL. Hudson BD, et al. Among authors: granzier hl. J Mol Cell Cardiol. 2010 May;48(5):972-8. doi: 10.1016/j.yjmcc.2009.12.006. Epub 2009 Dec 21. J Mol Cell Cardiol. 2010. PMID: 20026128 Free PMC article.

8

Calcium sensitivity and the Frank-Starling mechanism of the heart are increased in titin N2B region-deficient mice.

Lee EJ, Peng J, Radke M, Gotthardt M, Granzier HL. Lee EJ, et al. Among authors: granzier hl. J Mol Cell Cardiol. 2010 Sep;49(3):449-58. doi: 10.1016/j.yjmcc.2010.05.006. Epub 2010 May 23. J Mol Cell Cardiol. 2010. PMID: 20507834 Free PMC article.

9

Titin based viscosity in ventricular physiology: an integrative investigation of PEVK-actin interactions.

Chung CS, Methawasin M, Nelson OL, Radke MH, Hidalgo CG, Gotthardt M, Granzier HL. Chung CS, et al. Among authors: granzier hl. J Mol Cell Cardiol. 2011 Sep;51(3):428-34. doi: 10.1016/j.yjmcc.2011.06.006. Epub 2011 Jun 16. J Mol Cell Cardiol. 2011. PMID: 21708170 Free PMC article.

10

Mechanics on myocardium deficient in the N2B region of titin: the cardiac-unique spring element improves efficiency of the cardiac cycle.

Nedrud J, Labeit S, Gotthardt M, Granzier H. Nedrud J, et al. Biophys J. 2011 Sep 21;101(6):1385-92. doi: 10.1016/j.bpj.2011.06.054. Epub 2011 Sep 20. Biophys J. 2011. PMID: 21943419 Free PMC article.

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