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Small soluble α-synuclein aggregates are the toxic species in Parkinson's disease.
Emin D, Zhang YP, Lobanova E, Miller A, Li X, Xia Z, Dakin H, Sideris DI, Lam JYL, Ranasinghe RT, Kouli A, Zhao Y, De S, Knowles TPJ, Vendruscolo M, Ruggeri FS, Aigbirhio FI, Williams-Gray CH, Klenerman D. Emin D, et al. Among authors: zhang yp. Nat Commun. 2022 Sep 20;13(1):5512. doi: 10.1038/s41467-022-33252-6. Nat Commun. 2022. PMID: 36127374 Free PMC article.
Cerebral organoids with chromosome 21 trisomy secrete Alzheimer's disease-related soluble aggregates detectable by single-molecule-fluorescence and super-resolution microscopy.
Fertan E, Böken D, Murray A, Danial JSH, Lam JYL, Wu Y, Goh PA, Alić I, Cheetham MR, Lobanova E, Zhang YP, Nižetić D, Klenerman D. Fertan E, et al. Among authors: zhang yp. Mol Psychiatry. 2024 Feb;29(2):369-386. doi: 10.1038/s41380-023-02333-3. Epub 2023 Dec 15. Mol Psychiatry. 2024. PMID: 38102482 Free PMC article.
Co-aggregation with Apolipoprotein E modulates the function of Amyloid-β in Alzheimer's disease.
Xia Z, Prescott EE, Urbanek A, Wareing HE, King MC, Olerinyova A, Dakin H, Leah T, Barnes KA, Matuszyk MM, Dimou E, Hidari E, Zhang YP, Lam JYL, Danial JSH, Strickland MR, Jiang H, Thornton P, Crowther DC, Ohtonen S, Gómez-Budia M, Bell SM, Ferraiuolo L, Mortiboys H, Higginbottom A, Wharton SB, Holtzman DM, Malm T, Ranasinghe RT, Klenerman D, De S. Xia Z, et al. Among authors: zhang yp. Nat Commun. 2024 Jun 1;15(1):4695. doi: 10.1038/s41467-024-49028-z. Nat Commun. 2024. PMID: 38824138 Free PMC article.
Improved Imaging Surface for Quantitative Single-Molecule Microscopy.
Zhang YP, Lobanova E, Dworkin A, Furlepa M, Yang WS, Burke M, Meng JX, Potter N, Sala RL, Kahanawita L, Layburn F, Scherman OA, Williams-Gray CH, Klenerman D. Zhang YP, et al. ACS Appl Mater Interfaces. 2024 Jul 17;16(28):37255-37264. doi: 10.1021/acsami.4c06512. Epub 2024 Jul 9. ACS Appl Mater Interfaces. 2024. PMID: 38979642 Free PMC article.
254,626 results
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