Wrennall JA - Search Results

1

SPLUNC1 is a negative regulator of the Orai1 Ca²⁺ channel.

Wu T, Goriounova AS, Worthington EN, Wrennall JA, Ghosh A, Ahmad S, Flori Sassano M, Tarran R. Wu T, et al. Among authors: wrennall ja. Physiol Rep. 2022 May;10(10):e15306. doi: 10.14814/phy2.15306. Physiol Rep. 2022. PMID: 35581745 Free PMC article.

2

Chronic E-Cigarette Exposure Alters Human Alveolar Macrophage Morphology and Gene Expression.

Davis ES, Ghosh A, Coakley RD, Wrennall JA, Lubamba BA, Rowell TR, Dang H, Pawlak EA, Li Q, Alexis NE, Ribeiro CMP, Tarran R. Davis ES, et al. Among authors: wrennall ja. Nicotine Tob Res. 2022 Feb 14;24(3):395-399. doi: 10.1093/ntr/ntab186. Nicotine Tob Res. 2022. PMID: 34519792 Free PMC article.

3

Combustible and Electronic Cigarette Exposures Increase ACE2 Activity and SARS-CoV-2 Spike Binding.

Ghosh A, Girish V, Yuan ML, Coakley RD, Wrennall JA, Alexis NE, Sausville EL, Vasudevan A, Chait AR, Sheltzer JM, Tarran R. Ghosh A, et al. Among authors: wrennall ja. Am J Respir Crit Care Med. 2022 Jan 1;205(1):129-133. doi: 10.1164/rccm.202106-1377LE. Am J Respir Crit Care Med. 2022. PMID: 34748720 Free PMC article. No abstract available.

4

A SPLUNC1 Peptidomimetic Inhibits Orai1 and Reduces Inflammation in a Murine Allergic Asthma Model.

Wrennall JA, Ahmad S, Worthington EN, Wu T, Goriounova AS, Voeller AS, Stewart IE, Ghosh A, Krajewski K, Tilley SL, Hickey AJ, Sassano MF, Tarran R. Wrennall JA, et al. Am J Respir Cell Mol Biol. 2022 Mar;66(3):271-282. doi: 10.1165/rcmb.2020-0452OC. Am J Respir Cell Mol Biol. 2022. PMID: 34807800 Free PMC article.

5

Super resolution microscopy analysis reveals increased Orai1 activity in asthma and cystic fibrosis lungs.

Goriounova AS, Gilmore RC, Wrennall JA, Tarran R. Goriounova AS, et al. Among authors: wrennall ja. J Cyst Fibros. 2023 Jan;22(1):161-171. doi: 10.1016/j.jcf.2022.07.003. Epub 2022 Aug 10. J Cyst Fibros. 2023. PMID: 35961837 Free PMC article.

6

Vaping additives cannabinoid oil and vitamin E acetate adhere to and damage the human airway epithelium.

Reidel B, Abdelwahab S, Wrennall JA, Clapp PW, Beers JL, Jackson KD, Tarran R, Kesimer M. Reidel B, et al. Among authors: wrennall ja. J Appl Toxicol. 2023 May;43(5):680-693. doi: 10.1002/jat.4415. Epub 2022 Nov 30. J Appl Toxicol. 2023. PMID: 36372912 Free PMC article.

7

Passaging Primary Human Bronchial Epithelia Reduces CFTR-Mediated Fluid Transport and Alters mRNA Expression.

Wu T, Wrennall JA, Dang H, Baines DL, Tarran R. Wu T, et al. Among authors: wrennall ja. Cells. 2023 Mar 24;12(7):997. doi: 10.3390/cells12070997. Cells. 2023. PMID: 37048070 Free PMC article.

8

Specific Inhibition of Orai1-mediated Calcium Signalling Resolves Inflammation and Clears Bacteria in an Acute Respiratory Distress Syndrome Model.

Ahmad S, Wrennall JA, Goriounova AS, Sekhri M, Iskarpatyoti JA, Ghosh A, Abdelwahab SH, Voeller A, Rai M, Mahida RY, Krajewski K, Ignar DM, Greenbaum A, Moran TP, Tilley SL, Thickett DR, Sassano MF, Tarran R. Ahmad S, et al. Among authors: wrennall ja. Am J Respir Crit Care Med. 2024 Mar 15;209(6):703-715. doi: 10.1164/rccm.202308-1393OC. Am J Respir Crit Care Med. 2024. PMID: 37972349

9

ELD607 specifically traffics Orai1 to the lysosome leading to inhibition of store operated calcium entry.

Goriounova AS, Flori Sassano M, Wrennall JA, Tarran R. Goriounova AS, et al. Among authors: wrennall ja. Cell Calcium. 2024 Nov;123:102945. doi: 10.1016/j.ceca.2024.102945. Epub 2024 Aug 14. Cell Calcium. 2024. PMID: 39191091 Free article.

10

Pulmonary-delivered Anticalin Jagged-1 antagonists reduce experimental airway mucus hyperproduction and obstruction.

Heinzelmann K, Fysikopoulos A, Jaquin TJ, Peper-Gabriel JK, Hansbauer EM, Grüner S, Prassler J, Wurzenberger C, Kennedy JGC, Snead JY, Wrennall JA, Heinig K, Wurzenberger C, Bel Aiba RS, Tarran R, Livraghi-Butrico A, Fitzgerald MF, Anderson GP, Rothe C, Matschiner G, Olwill SA, Hagner M. Heinzelmann K, et al. Among authors: wrennall ja. Am J Physiol Lung Cell Mol Physiol. 2025 Jan 1;328(1):L75-L92. doi: 10.1152/ajplung.00059.2024. Epub 2024 Nov 5. Am J Physiol Lung Cell Mol Physiol. 2025. PMID: 39499257

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