Wang X - Search Results

1

Genome-wide gain-of-function screening identifies EZH2 mediating resistance to PI3Kα inhibitors in oesophageal squamous cell carcinoma.

Xing H, Gao M, Wang Y, Zhang X, Shi J, Wang X, Liu X, Ma Q, Kong X, Yang C, Ding J, Meng L. Xing H, et al. Among authors: wang x, wang y. Clin Transl Med. 2022 May;12(5):e835. doi: 10.1002/ctm2.835. Clin Transl Med. 2022. PMID: 35604910 Free PMC article.

2

WJD008, a dual phosphatidylinositol 3-kinase (PI3K)/mammalian target of rapamycin inhibitor, prevents PI3K signaling and inhibits the proliferation of transformed cells with oncogenic PI3K mutant.

Li T, Wang J, Wang X, Yang N, Chen SM, Tong LJ, Yang CH, Meng LH, Ding J. Li T, et al. Among authors: wang x, wang j. J Pharmacol Exp Ther. 2010 Sep 1;334(3):830-8. doi: 10.1124/jpet.110.167940. Epub 2010 Jun 3. J Pharmacol Exp Ther. 2010. PMID: 20522531

3

Discovery and bioactivity of 4-(2-arylpyrido[3',2':3,4]pyrrolo[1,2-f][1,2,4]triazin-4-yl) morpholine derivatives as novel PI3K inhibitors.

Wang J, Wang X, Chen Y, Chen S, Chen G, Tong L, Meng L, Xie Y, Ding J, Yang C. Wang J, et al. Among authors: wang x. Bioorg Med Chem Lett. 2012 Jan 1;22(1):339-42. doi: 10.1016/j.bmcl.2011.11.003. Epub 2011 Nov 9. Bioorg Med Chem Lett. 2012. PMID: 22130133

4

Inhibition of tumor cell growth, proliferation and migration by X-387, a novel active-site inhibitor of mTOR.

Chen SM, Liu JL, Wang X, Liang C, Ding J, Meng LH. Chen SM, et al. Among authors: wang x. Biochem Pharmacol. 2012 May 1;83(9):1183-94. doi: 10.1016/j.bcp.2012.01.019. Epub 2012 Jan 26. Biochem Pharmacol. 2012. PMID: 22305748

5

Inhibition of chemokine (CXC motif) ligand 12/chemokine (CXC motif) receptor 4 axis (CXCL12/CXCR4)-mediated cell migration by targeting mammalian target of rapamycin (mTOR) pathway in human gastric carcinoma cells.

Chen G, Chen SM, Wang X, Ding XF, Ding J, Meng LH. Chen G, et al. Among authors: wang x. J Biol Chem. 2012 Apr 6;287(15):12132-41. doi: 10.1074/jbc.M111.302299. Epub 2012 Feb 15. J Biol Chem. 2012. PMID: 22337890 Free PMC article.

6

A pharmacological model reveals biased dependency on PI3K isoforms for tumor cell growth.

Wang X, Li JP, Yang Y, Ding J, Meng LH. Wang X, et al. Acta Pharmacol Sin. 2013 Sep;34(9):1201-7. doi: 10.1038/aps.2013.81. Epub 2013 Jul 29. Acta Pharmacol Sin. 2013. PMID: 23892273 Free PMC article.

7

DW09849, a selective phosphatidylinositol 3-kinase (PI3K) inhibitor, prevents PI3K signaling and preferentially inhibits proliferation of cells containing the oncogenic mutation p110α (H1047R).

Liu JL, Gao GR, Zhang X, Cao SF, Guo CL, Wang X, Tong LJ, Ding J, Duan WH, Meng LH. Liu JL, et al. Among authors: wang x. J Pharmacol Exp Ther. 2014 Mar;348(3):432-41. doi: 10.1124/jpet.113.210724. Epub 2013 Dec 20. J Pharmacol Exp Ther. 2014. PMID: 24361696

8

Simultaneous targeting of PI3Kδ and a PI3Kδ-dependent MEK1/2-Erk1/2 pathway for therapy in pediatric B-cell acute lymphoblastic leukemia.

Wang X, Zhang X, Li BS, Zhai X, Yang Z, Ding LX, Wang H, Liang C, Zhu W, Ding J, Meng LH. Wang X, et al. Among authors: wang h. Oncotarget. 2014 Nov 15;5(21):10732-44. doi: 10.18632/oncotarget.2533. Oncotarget. 2014. PMID: 25313141 Free PMC article.

9

Targeting PI3Kδ: emerging therapy for chronic lymphocytic leukemia and beyond.

Wei M, Wang X, Song Z, Jiao M, Ding J, Meng LH, Zhang A. Wei M, et al. Among authors: wang x. Med Res Rev. 2015 Jul;35(4):720-52. doi: 10.1002/med.21341. Epub 2015 Mar 11. Med Res Rev. 2015. PMID: 25763934 Review.

10

PI3K isoform-selective inhibitors: next-generation targeted cancer therapies.

Wang X, Ding J, Meng LH. Wang X, et al. Acta Pharmacol Sin. 2015 Oct;36(10):1170-6. doi: 10.1038/aps.2015.71. Epub 2015 Sep 14. Acta Pharmacol Sin. 2015. PMID: 26364801 Free PMC article. Review.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

210,068 results

Search Page

Filters