Anoctamin 1 controls bone resorption by coupling Cl- channel activation with RANKL-RANK signaling transduction.
Sun W, Guo S, Li Y, Li J, Liu C, Chen Y, Wang X, Tan Y, Tian H, Wang C, Du R, Zhong G, Shi S, Ma B, Qu C, Fu J, Jin X, Zhao D, Zhan Y, Ling S, An H, Li Y.
Sun W, et al. Among authors: an h.
Nat Commun. 2022 May 24;13(1):2899. doi: 10.1038/s41467-022-30625-9.
Nat Commun. 2022.
PMID: 35610255
Free PMC article.
The calcium-activated chloride channel Anoctamin 1 (also known as TMEM16A) is an important chloride channel involved in many physiological processes. However, its role in osteoclast remains unresolved. ...These results collectively establish Anoctamin 1 as an essent …
The calcium-activated chloride channel Anoctamin 1 (also known as TMEM16A) is an important chloride channel involved in many physiolo …