Insulin and IGF1 receptors are essential for the development and steroidogenic function of adult Leydig cells.
Neirijnck Y, Calvel P, Kilcoyne KR, Kühne F, Stévant I, Griffeth RJ, Pitetti JL, Andric SA, Hu MC, Pralong F, Smith LB, Nef S.
Neirijnck Y, et al.
FASEB J. 2018 Jun;32(6):3321-3335. doi: 10.1096/fj.201700769RR. Epub 2018 Jan 24.
FASEB J. 2018.
PMID: 29401624
Taken together, these data reveal the cell-autonomous and nonautonomous roles of the IGF system for proper development and maintenance of steroidogenic lineages.-Neirijnck, Y., Calvel, P., Kilcoyne, K. R., Kuhne, F., Stevant, I., Griffeth, R. J., Pitetti, J....
Taken together, these data reveal the cell-autonomous and nonautonomous roles of the IGF system for proper development and maintenance of st …