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Transcriptional profiling of human Vδ1 T cells reveals a pathogen-driven adaptive differentiation program.
McMurray JL, von Borstel A, Taher TE, Syrimi E, Taylor GS, Sharif M, Rossjohn J, Remmerswaal EBM, Bemelman FJ, Vieira Braga FA, Chen X, Teichmann SA, Mohammed F, Berry AA, Lyke KE, Williamson KC, Stubbington MJT, Davey MS, Willcox CR, Willcox BE. McMurray JL, et al. Among authors: rossjohn j. Cell Rep. 2022 May 24;39(8):110858. doi: 10.1016/j.celrep.2022.110858. Cell Rep. 2022. PMID: 35613583 Free PMC article.
Targeted suppression of autoreactive CD8+ T-cell activation using blocking anti-CD8 antibodies.
Clement M, Pearson JA, Gras S, van den Berg HA, Lissina A, Llewellyn-Lacey S, Willis MD, Dockree T, McLaren JE, Ekeruche-Makinde J, Gostick E, Robertson NP, Rossjohn J, Burrows SR, Price DA, Wong FS, Peakman M, Skowera A, Wooldridge L. Clement M, et al. Among authors: rossjohn j. Sci Rep. 2016 Oct 17;6:35332. doi: 10.1038/srep35332. Sci Rep. 2016. PMID: 27748447 Free PMC article.
Chronic Inflammation Permanently Reshapes Tissue-Resident Immunity in Celiac Disease.
Mayassi T, Ladell K, Gudjonson H, McLaren JE, Shaw DG, Tran MT, Rokicka JJ, Lawrence I, Grenier JC, van Unen V, Ciszewski C, Dimaano M, Sayegh HE, Kumar V, Wijmenga C, Green PHR, Gokhale R, Jericho H, Semrad CE, Guandalini S, Dinner AR, Kupfer SS, Reid HH, Barreiro LB, Rossjohn J, Price DA, Jabri B. Mayassi T, et al. Among authors: rossjohn j. Cell. 2019 Feb 21;176(5):967-981.e19. doi: 10.1016/j.cell.2018.12.039. Epub 2019 Feb 7. Cell. 2019. PMID: 30739797 Free PMC article.
A class of γδ T cell receptors recognize the underside of the antigen-presenting molecule MR1.
Le Nours J, Gherardin NA, Ramarathinam SH, Awad W, Wiede F, Gully BS, Khandokar Y, Praveena T, Wubben JM, Sandow JJ, Webb AI, von Borstel A, Rice MT, Redmond SJ, Seneviratna R, Sandoval-Romero ML, Li S, Souter MNT, Eckle SBG, Corbett AJ, Reid HH, Liu L, Fairlie DP, Giles EM, Westall GP, Tothill RW, Davey MS, Berry R, Tiganis T, McCluskey J, Pellicci DG, Purcell AW, Uldrich AP, Godfrey DI, Rossjohn J. Le Nours J, et al. Among authors: rossjohn j. Science. 2019 Dec 20;366(6472):1522-1527. doi: 10.1126/science.aav3900. Science. 2019. PMID: 31857486
Cross-Reactive Donor-Specific CD8+ Tregs Efficiently Prevent Transplant Rejection.
Picarda E, Bézie S, Usero L, Ossart J, Besnard M, Halim H, Echasserieau K, Usal C, Rossjohn J, Bernardeau K, Gras S, Guillonneau C. Picarda E, et al. Among authors: rossjohn j. Cell Rep. 2019 Dec 24;29(13):4245-4255.e6. doi: 10.1016/j.celrep.2019.11.106. Cell Rep. 2019. PMID: 31875536 Free article.
Virus-Mediated Suppression of the Antigen Presentation Molecule MR1.
McSharry BP, Samer C, McWilliam HEG, Ashley CL, Yee MB, Steain M, Liu L, Fairlie DP, Kinchington PR, McCluskey J, Abendroth A, Villadangos JA, Rossjohn J, Slobedman B. McSharry BP, et al. Among authors: rossjohn j. Cell Rep. 2020 Mar 3;30(9):2948-2962.e4. doi: 10.1016/j.celrep.2020.02.017. Cell Rep. 2020. PMID: 32130899 Free PMC article.
Absence of mucosal-associated invariant T cells in a person with a homozygous point mutation in MR1.
Howson LJ, Awad W, von Borstel A, Lim HJ, McWilliam HEG, Sandoval-Romero ML, Majumdar S, Hamzeh AR, Andrews TD, McDermott DH, Murphy PM, Le Nours J, Mak JYW, Liu L, Fairlie DP, McCluskey J, Villadangos JA, Cook MC, Turner SJ, Davey MS, Ojaimi S, Rossjohn J. Howson LJ, et al. Among authors: rossjohn j. Sci Immunol. 2020 Jul 24;5(49):eabc9492. doi: 10.1126/sciimmunol.abc9492. Sci Immunol. 2020. PMID: 32709702 Free PMC article.
536 results