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Catalytic inhibition of KAT6/KAT7 enhances the efficacy and overcomes primary and acquired resistance to Menin inhibitors in MLL leukaemia.
Gordon SJV, Perner F, MacPherson L, Wenge DV, Bourgeois W, Fennell K, Klaus T, Petrovic J, Horvath J, Cao J, Lapek J, Uryu S, White J, Lam EYN, Mu XJ, Chan YC, Gillespie A, Blyth B, Camerino MA, Bozikis YE, Holze H, Knezevic K, Balic J, Stupple PA, Street IP, Monahan BJ, Sharma S, Wainwright EN, Vassiliadis D, Paul TA, Armstrong SA, Dawson MA. Gordon SJV, et al. Among authors: armstrong sa. bioRxiv [Preprint]. 2024 Dec 12:2024.12.11.627663. doi: 10.1101/2024.12.11.627663. bioRxiv. 2024. PMID: 39713447 Free PMC article. Preprint.
Epigenetic Therapies.
Bourgeois W, Armstrong SA, Heikamp EB. Bourgeois W, et al. Among authors: armstrong sa. Cold Spring Harb Perspect Med. 2024 Dec 18:a041637. doi: 10.1101/cshperspect.a041637. Online ahead of print. Cold Spring Harb Perspect Med. 2024. PMID: 39694694
PD-1 and CD73 on naive CD4+ T cells synergistically limit responses to self.
Nettersheim FS, Brunel S, Sinkovits RS, Armstrong SS, Roy P, Billitti M, Kobiyama K, Alimadadi A, Bombin S, Lu L, Zoccheddu M, Oliaeimotlagh M, Benedict CA, Sette A, Ley K. Nettersheim FS, et al. Among authors: armstrong ss. Nat Immunol. 2024 Nov 21. doi: 10.1038/s41590-024-02021-6. Online ahead of print. Nat Immunol. 2024. PMID: 39572641
1,608 results