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Page 1
Disarming an Electrophilic Warhead: Retaining Potency in Tyrosine Kinase Inhibitor (TKI)-Resistant CML Lines While Circumventing Pharmacokinetic Liabilities.
Ali AM, Gómez-Biagi RF, Rosa DA, Lai PS, Heaton WL, Park JS, Eiring AM, Vellore NA, de Araujo ED, Ball DP, Shouksmith AE, Patel AB, Deininger MW, O'Hare T, Gunning PT. Ali AM, et al. Among authors: gunning pt. ChemMedChem. 2016 Apr 19;11(8):850-61. doi: 10.1002/cmdc.201600021. Epub 2016 Mar 30. ChemMedChem. 2016. PMID: 27028877 Free PMC article.
CD133+ brain tumor-initiating cells are dependent on STAT3 signaling to drive medulloblastoma recurrence.
Garg N, Bakhshinyan D, Venugopal C, Mahendram S, Rosa DA, Vijayakumar T, Manoranjan B, Hallett R, McFarlane N, Delaney KH, Kwiecien JM, Arpin CC, Lai PS, Gómez-Biagi RF, Ali AM, de Araujo ED, Ajani OA, Hassell JA, Gunning PT, Singh SK. Garg N, et al. Among authors: gunning pt. Oncogene. 2017 Feb 2;36(5):606-617. doi: 10.1038/onc.2016.235. Epub 2016 Oct 24. Oncogene. 2017. PMID: 27775079 Free PMC article.
ProxyPhos sensors for the detection of negatively charged membranes.
Murcar-Evans BI, Cabral AD, Toutah K, de Araujo ED, Lai A, Macdonald PM, Berger-Becvar A, Kraskouskaya D, Gunning PT. Murcar-Evans BI, et al. Among authors: gunning pt. Analyst. 2017 Nov 20;142(23):4511-4521. doi: 10.1039/c7an00568g. Analyst. 2017. PMID: 29098228
Pharmacologic inhibition of STAT5 in acute myeloid leukemia.
Wingelhofer B, Maurer B, Heyes EC, Cumaraswamy AA, Berger-Becvar A, de Araujo ED, Orlova A, Freund P, Ruge F, Park J, Tin G, Ahmar S, Lardeau CH, Sadovnik I, Bajusz D, Keserű GM, Grebien F, Kubicek S, Valent P, Gunning PT, Moriggl R. Wingelhofer B, et al. Among authors: gunning pt. Leukemia. 2018 May;32(5):1135-1146. doi: 10.1038/s41375-017-0005-9. Epub 2018 Feb 2. Leukemia. 2018. PMID: 29472718 Free PMC article.
A functional in vitro assay for screening inhibitors of STAT5B phosphorylation.
de Araujo ED, Manaswiyoungkul P, Erdogan F, Qadree AK, Sina D, Tin G, Toutah K, Yuen K, Gunning PT. de Araujo ED, et al. Among authors: gunning pt. J Pharm Biomed Anal. 2019 Jan 5;162:60-65. doi: 10.1016/j.jpba.2018.08.036. Epub 2018 Aug 18. J Pharm Biomed Anal. 2019. PMID: 30223143
128 results