BKCa compensates impaired coronary vasoreactivity through RhoA/ROCK pathway in hind-limb unweighted rats.
Wu Y, Yue Z, Wang Q, Lv Q, Liu H, Bai Y, Li S, Xie M, Bao J, Ma J, Wang Z, Zhu X.
Wu Y, et al. Among authors: liu h.
FASEB J. 2019 Dec;33(12):13358-13366. doi: 10.1096/fj.201901273R. Epub 2019 Sep 17.
FASEB J. 2019.
PMID: 31530101
These results indicate that HU impairs coronary vasoconstriction but enhances BK(Ca) activity acting as a protective mechanism avoiding excessive decrease of coronary vasoreactivity through activation of the RhoA/ROCK pathway.-Wu, Y., Yue, Z., Wang, Q., Lv, Q., Liu, H …
These results indicate that HU impairs coronary vasoconstriction but enhances BK(Ca) activity acting as a protective mechanism avoiding exce …