Shang L - Search Results

1

The structure-based design of peptidomimetic inhibitors against SARS-CoV-2 3C like protease as Potent anti-viral drug candidate.

Wang H, Pei R, Li X, Deng W, Xing S, Zhang Y, Zhang C, He S, Sun H, Xiao S, Xiong J, Zhang Y, Chen X, Wang Y, Guo Y, Zhang B, Shang L. Wang H, et al. Among authors: shang l. Eur J Med Chem. 2022 Aug 5;238:114458. doi: 10.1016/j.ejmech.2022.114458. Epub 2022 May 13. Eur J Med Chem. 2022. PMID: 35635946 Free PMC article.

2

Biochemical characterization of recombinant Enterovirus 71 3C protease with fluorogenic model peptide substrates and development of a biochemical assay.

Shang L, Zhang S, Yang X, Sun J, Li L, Cui Z, He Q, Guo Y, Sun Y, Yin Z. Shang L, et al. Antimicrob Agents Chemother. 2015 Apr;59(4):1827-36. doi: 10.1128/AAC.04698-14. Epub 2014 Nov 24. Antimicrob Agents Chemother. 2015. PMID: 25421478 Free PMC article.

3

An adenosine nucleoside analogue NITD008 inhibits EV71 proliferation.

Shang L, Wang Y, Qing J, Shu B, Cao L, Lou Z, Gong P, Sun Y, Yin Z. Shang L, et al. Antiviral Res. 2014 Dec;112:47-58. doi: 10.1016/j.antiviral.2014.10.009. Epub 2014 Oct 23. Antiviral Res. 2014. PMID: 25446894

4

Cyanohydrin as an Anchoring Group for Potent and Selective Inhibitors of Enterovirus 71 3C Protease.

Zhai Y, Zhao X, Cui Z, Wang M, Wang Y, Li L, Sun Q, Yang X, Zeng D, Liu Y, Sun Y, Lou Z, Shang L, Yin Z. Zhai Y, et al. Among authors: shang l. J Med Chem. 2015 Dec 10;58(23):9414-20. doi: 10.1021/acs.jmedchem.5b01013. Epub 2015 Nov 25. J Med Chem. 2015. PMID: 26571192

5

A Conserved Inhibitory Mechanism of a Lycorine Derivative against Enterovirus and Hepatitis C Virus.

Guo Y, Wang Y, Cao L, Wang P, Qing J, Zheng Q, Shang L, Yin Z, Sun Y. Guo Y, et al. Among authors: shang l. Antimicrob Agents Chemother. 2015 Nov 23;60(2):913-24. doi: 10.1128/AAC.02274-15. Print 2016 Feb. Antimicrob Agents Chemother. 2015. PMID: 26596952 Free PMC article.

6

Synthesis and structure-activity relationship of α-keto amides as enterovirus 71 3C protease inhibitors.

Zeng D, Ma Y, Zhang R, Nie Q, Cui Z, Wang Y, Shang L, Yin Z. Zeng D, et al. Among authors: shang l. Bioorg Med Chem Lett. 2016 Apr 1;26(7):1762-6. doi: 10.1016/j.bmcl.2016.02.039. Epub 2016 Feb 16. Bioorg Med Chem Lett. 2016. PMID: 26916437

7

The discovery of indole derivatives as novel hepatitis C virus inhibitors.

Han Z, Liang X, Wang Y, Qing J, Cao L, Shang L, Yin Z. Han Z, et al. Among authors: shang l. Eur J Med Chem. 2016 Jun 30;116:147-155. doi: 10.1016/j.ejmech.2016.03.062. Epub 2016 Mar 26. Eur J Med Chem. 2016. PMID: 27061978

8

Structure-activity relationship study of peptidomimetic aldehydes as enterovirus 71 3C protease inhibitors.

Zhai Y, Ma Y, Ma F, Nie Q, Ren X, Wang Y, Shang L, Yin Z. Zhai Y, et al. Among authors: shang l. Eur J Med Chem. 2016 Nov 29;124:559-573. doi: 10.1016/j.ejmech.2016.08.064. Epub 2016 Aug 28. Eur J Med Chem. 2016. PMID: 27614190

9

Inhibition of enterovirus 71 replication by an α-hydroxy-nitrile derivative NK-1.9k.

Wang Y, Cao L, Zhai Y, Ma J, Nie Q, Li T, Yin Z, Sun Y, Shang L. Wang Y, et al. Among authors: shang l. Antiviral Res. 2017 May;141:91-100. doi: 10.1016/j.antiviral.2017.01.002. Epub 2017 Jan 5. Antiviral Res. 2017. PMID: 28063993

10

Structure of the Enterovirus 71 3C Protease in Complex with NK-1.8k and Indications for the Development of Antienterovirus Protease Inhibitor.

Wang Y, Cao L, Zhai Y, Yin Z, Sun Y, Shang L. Wang Y, et al. Among authors: shang l. Antimicrob Agents Chemother. 2017 Jun 27;61(7):e00298-17. doi: 10.1128/AAC.00298-17. Print 2017 Jul. Antimicrob Agents Chemother. 2017. PMID: 28461310 Free PMC article.

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