Radi M - Search Results

1

Towards Innovative Antibacterial Correctors for Cystic Fibrosis Targeting the Lung Microbiome with a Multifunctional Effect.

Martina MG, Sannio F, Crespan E, Pavone M, Simoncini A, Barbieri F, Perini C, Pesce E, Maga G, Pedemonte N, Docquier JD, Radi M. Martina MG, et al. Among authors: radi m. ChemMedChem. 2022 Sep 5;17(17):e202200277. doi: 10.1002/cmdc.202200277. Epub 2022 Jun 23. ChemMedChem. 2022. PMID: 35638249

2

Parallel solution-phase synthesis of 4-dialkylamino-2-methylsulfonyl-6-vinylpyrimidines.

Radi M, Petricci E, Maga G, Corelli F, Botta M. Radi M, et al. J Comb Chem. 2005 Jan-Feb;7(1):117-22. doi: 10.1021/cc049880u. J Comb Chem. 2005. PMID: 15638490

3

Discovery of non-nucleoside inhibitors of HIV-1 reverse transcriptase competing with the nucleotide substrate.

Maga G, Radi M, Zanoli S, Manetti F, Cancio R, Hübscher U, Spadari S, Falciani C, Terrazas M, Vilarrasa J, Botta M. Maga G, et al. Among authors: radi m. Angew Chem Int Ed Engl. 2007;46(11):1810-3. doi: 10.1002/anie.200604165. Angew Chem Int Ed Engl. 2007. PMID: 17274083 No abstract available.

4

Discovery and SAR of 1,3,4-thiadiazole derivatives as potent Abl tyrosine kinase inhibitors and cytodifferentiating agents.

Radi M, Crespan E, Botta G, Falchi F, Maga G, Manetti F, Corradi V, Mancini M, Santucci MA, Schenone S, Botta M. Radi M, et al. Bioorg Med Chem Lett. 2008 Feb 1;18(3):1207-11. doi: 10.1016/j.bmcl.2007.11.112. Epub 2007 Dec 4. Bioorg Med Chem Lett. 2008. PMID: 18078752

5

A multidisciplinary approach for the identification of novel HIV-1 non-nucleoside reverse transcriptase inhibitors: S-DABOCs and DAVPs.

Radi M, Falciani C, Contemori L, Petricci E, Maga G, Samuele A, Zanoli S, Terrazas M, Castria M, Togninelli A, Esté JA, Clotet-Codina I, Armand-Ugón M, Botta M. Radi M, et al. ChemMedChem. 2008 Apr;3(4):573-93. doi: 10.1002/cmdc.200700198. ChemMedChem. 2008. PMID: 18081133

6

Towards novel S-DABOC inhibitors: synthesis, biological investigation, and molecular modeling studies.

Radi M, Angeli L, Franchi L, Contemori L, Maga G, Samuele A, Zanoli S, Armand-Ugon M, Gonzalez E, Llano A, Esté JA, Botta M. Radi M, et al. Bioorg Med Chem Lett. 2008 Nov 1;18(21):5777-80. doi: 10.1016/j.bmcl.2008.09.070. Epub 2008 Sep 23. Bioorg Med Chem Lett. 2008. PMID: 18842407

7

Crystal structure of HIV-1 reverse transcriptase bound to a non-nucleoside inhibitor with a novel mechanism of action.

Freisz S, Bec G, Radi M, Wolff P, Crespan E, Angeli L, Dumas P, Maga G, Botta M, Ennifar E. Freisz S, et al. Among authors: radi m. Angew Chem Int Ed Engl. 2010 Mar 1;49(10):1805-8. doi: 10.1002/anie.200905651. Angew Chem Int Ed Engl. 2010. PMID: 20135654 No abstract available.

8

Dual Src and Abl inhibitors target wild type Abl and the AblT315I Imatinib-resistant mutant with different mechanisms.

Crespan E, Radi M, Zanoli S, Schenone S, Botta M, Maga G. Crespan E, et al. Among authors: radi m. Bioorg Med Chem. 2010 Jun 1;18(11):3999-4008. doi: 10.1016/j.bmc.2010.04.024. Epub 2010 Apr 18. Bioorg Med Chem. 2010. PMID: 20451394

9

Design and synthesis of thiadiazoles and thiazoles targeting the Bcr-Abl T315I mutant: from docking false positives to ATP-noncompetitive inhibitors.

Radi M, Crespan E, Falchi F, Bernardo V, Zanoli S, Manetti F, Schenone S, Maga G, Botta M. Radi M, et al. ChemMedChem. 2010 Aug 2;5(8):1226-31. doi: 10.1002/cmdc.201000066. ChemMedChem. 2010. PMID: 20509136 No abstract available.

10

Design, synthesis, biological activity, and ADME properties of pyrazolo[3,4-d]pyrimidines active in hypoxic human leukemia cells: a lead optimization study.

Radi M, Dreassi E, Brullo C, Crespan E, Tintori C, Bernardo V, Valoti M, Zamperini C, Daigl H, Musumeci F, Carraro F, Naldini A, Filippi I, Maga G, Schenone S, Botta M. Radi M, et al. J Med Chem. 2011 Apr 28;54(8):2610-26. doi: 10.1021/jm1012819. Epub 2011 Mar 28. J Med Chem. 2011. PMID: 21443205

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