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SCR-7952, a highly selective MAT2A inhibitor, demonstrates synergistic antitumor activities in combination with the S-adenosylmethionine-competitive or the methylthioadenosine-cooperative protein arginine methyltransferase 5 inhibitors in methylthioadenosine phosphorylase-deleted tumors.
Yu Z, Kuang Y, Xue L, Ma X, Li T, Yuan L, Li M, Xue G, Li Z, Tang F, Tang J, Shan J, Wang W, Tang R, Zhou F. Yu Z, et al. Among authors: li t, li z, li m. MedComm (2020). 2024 Sep 20;5(10):e705. doi: 10.1002/mco2.705. eCollection 2024 Oct. MedComm (2020). 2024. PMID: 39309689 Free PMC article.
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