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Fibroblast-specific expression of a kinase-deficient type II transforming growth factor beta (TGFbeta) receptor leads to paradoxical activation of TGFbeta signaling pathways with fibrosis in transgenic mice.
Denton CP, Zheng B, Evans LA, Shi-wen X, Ong VH, Fisher I, Lazaridis K, Abraham DJ, Black CM, de Crombrugghe B. Denton CP, et al. Among authors: ong vh. J Biol Chem. 2003 Jul 4;278(27):25109-19. doi: 10.1074/jbc.M300636200. Epub 2003 Apr 21. J Biol Chem. 2003. PMID: 12707256 Free article.
Activation of key profibrotic mechanisms in transgenic fibroblasts expressing kinase-deficient type II Transforming growth factor-{beta} receptor (T{beta}RII{delta}k).
Denton CP, Lindahl GE, Khan K, Shiwen X, Ong VH, Gaspar NJ, Lazaridis K, Edwards DR, Leask A, Eastwood M, Leoni P, Renzoni EA, Bou Gharios G, Abraham DJ, Black CM. Denton CP, et al. Among authors: ong vh. J Biol Chem. 2005 Apr 22;280(16):16053-65. doi: 10.1074/jbc.M413134200. Epub 2005 Feb 11. J Biol Chem. 2005. PMID: 15708853 Free article.
Management of systemic sclerosis.
Ong VH, Brough G, Denton CP. Ong VH, et al. Clin Med (Lond). 2005 May-Jun;5(3):214-9. doi: 10.7861/clinmedicine.5-3-214. Clin Med (Lond). 2005. PMID: 16011210 Free PMC article. Review. No abstract available.
Innovative therapies for systemic sclerosis.
Ong VH, Denton CP. Ong VH, et al. Curr Opin Rheumatol. 2010 May;22(3):264-72. doi: 10.1097/BOR.0b013e328337c3d6. Curr Opin Rheumatol. 2010. PMID: 20190640 Review.
Biomarkers for skin involvement and fibrotic activity in scleroderma.
Moinzadeh P, Denton CP, Abraham D, Ong V, Hunzelmann N, Eckes B, Krieg T. Moinzadeh P, et al. J Eur Acad Dermatol Venereol. 2012 Mar;26(3):267-76. doi: 10.1111/j.1468-3083.2011.04206.x. Epub 2011 Aug 8. J Eur Acad Dermatol Venereol. 2012. PMID: 21819452 Review.
111 results