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Page 1
EWS::FLI1 and HOXD13 Control Tumor Cell Plasticity in Ewing Sarcoma.
Apfelbaum AA, Wu F, Hawkins AG, Magnuson B, Jiménez JA, Taylor SD, Wrenn ED, Waltner O, Pfaltzgraff ER, Song JY, Hall C, Wellik DM, Ljungman M, Furlan SN, Ryan RJH, Sarthy JF, Lawlor ER. Apfelbaum AA, et al. Among authors: ryan rjh. Clin Cancer Res. 2022 Oct 14;28(20):4466-4478. doi: 10.1158/1078-0432.CCR-22-0384. Clin Cancer Res. 2022. PMID: 35653119 Free PMC article.
ETV6 Deficiency Unlocks ERG-Dependent Microsatellite Enhancers to Drive Aberrant Gene Activation in B-Lymphoblastic Leukemia.
Kodgule R, Goldman JW, Monovich AC, Saari T, Aguilar AR, Hall CN, Rajesh N, Gupta J, Chu SA, Ye L, Gurumurthy A, Iyer A, Brown NA, Chiang MY, Cieslik MP, Ryan RJH. Kodgule R, et al. Among authors: ryan rjh. Blood Cancer Discov. 2023 Jan 6;4(1):34-53. doi: 10.1158/2643-3230.BCD-21-0224. Blood Cancer Discov. 2023. PMID: 36350827 Free PMC article.
Cdc73 protects Notch-induced T-cell leukemia cells from DNA damage and mitochondrial stress.
Melnick AF, Mullin C, Lin K, McCarter AC, Liang S, Liu YE, Wang Q, Jerome NA, Choe E, Kunnath N, Bodanapu G, Akter F, Magnuson B, Kumar S, Lombard DB, Muntean AG, Ljungman M, Sekiguchi J, Ryan RJH, Chiang MY. Melnick AF, et al. Among authors: ryan rjh. Blood. 2023 Dec 21;142(25):2159-2174. doi: 10.1182/blood.2023020144. Blood. 2023. PMID: 37616559 Free PMC article.
Cdc73 protects Notch-induced T-cell leukemia cells from DNA damage and mitochondrial stress.
Melnick A, Liang S, Liu Y, Wang Q, Dean N, Choe E, Kunnath N, Bodanapu G, Mullin C, Akter F, Lin K, Magnuson B, Kumar S, Lombard DB, Muntean AG, Ljungman M, Sekiguchi J, Ryan RJH, Chiang MY. Melnick A, et al. Among authors: ryan rjh. bioRxiv [Preprint]. 2023 Feb 4:2023.01.22.525059. doi: 10.1101/2023.01.22.525059. bioRxiv. 2023. Update in: Blood. 2023 Dec 21;142(25):2159-2174. doi: 10.1182/blood.2023020144 PMID: 36711472 Free PMC article. Updated. Preprint.
Selective Enhancer Gain-of-Function Deregulates MYC Expression in Multiple Myeloma.
Rahmat M, Clement K, Alberge JB, Sklavenitis-Pistofidis R, Kodgule R, Fulco CP, Heilpern-Mallory D, Nilsson K, Dorfman D, Engreitz JM, Getz G, Pinello L, Ryan RJH, Ghobrial IM. Rahmat M, et al. Among authors: ryan rjh. Cancer Res. 2024 Dec 16;84(24):4173-4183. doi: 10.1158/0008-5472.CAN-24-1440. Cancer Res. 2024. PMID: 39312195
Combinatorial ETS1-dependent control of oncogenic NOTCH1 enhancers in T-cell leukemia.
McCarter AC, Della Gatta G, Melnick A, Kim E, Sha C, Wang Q, Nalamolu JK, Liu Y, Keeley TM, Yan R, Sun M, Kodgule R, Kunnath N, Ambesi-Impiombato A, Kuick R, Rao A, Ryan RJH, Kee BL, Samuelson LC, Ostrowski MC, Ferrando AA, Chiang MY. McCarter AC, et al. Among authors: ryan rjh. Blood Cancer Discov. 2020 Sep;1(2):178-197. doi: 10.1158/2643-3230.BCD-20-0026. Blood Cancer Discov. 2020. PMID: 32924017 Free PMC article.
Selective Enhancer Dependencies in MYC -Intact and MYC -Rearranged Germinal Center B-cell Diffuse Large B-cell Lymphoma.
Iyer AR, Gurumurthy A, Kodgule R, Aguilar AR, Saari T, Ramzan A, Rausch D, Gupta J, Hall CN, Runge JS, Weiss M, Rahmat M, Anyoha R, Fulco CP, Ghobrial IM, Engreitz J, Cieslik MP, Ryan RJH. Iyer AR, et al. Among authors: ryan rjh. bioRxiv [Preprint]. 2023 May 3:2023.05.02.538892. doi: 10.1101/2023.05.02.538892. bioRxiv. 2023. PMID: 37205448 Free PMC article. Preprint.
Epigenomic mapping reveals distinct B cell acute lymphoblastic leukemia chromatin architectures and regulators.
Barnett KR, Mobley RJ, Diedrich JD, Bergeron BP, Bhattarai KR, Monovich AC, Narina S, Yang W, Crews KR, Manring CS, Jabbour E, Paietta E, Litzow MR, Kornblau SM, Stock W, Inaba H, Jeha S, Pui CH, Mullighan CG, Relling MV, Pruett-Miller SM, Ryan RJH, Yang JJ, Evans WE, Savic D. Barnett KR, et al. Among authors: ryan rjh. Cell Genom. 2023 Nov 20;3(12):100442. doi: 10.1016/j.xgen.2023.100442. eCollection 2023 Dec 13. Cell Genom. 2023. PMID: 38116118 Free PMC article.
30 results