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An innate IL-25-ILC2-MDSC axis creates a cancer-permissive microenvironment for Apc mutation-driven intestinal tumorigenesis.
Jou E, Rodriguez-Rodriguez N, Ferreira AF, Jolin HE, Clark PA, Sawmynaden K, Ko M, Murphy JE, Mannion J, Ward C, Matthews DJ, Buczacki SJA, McKenzie ANJ. Jou E, et al. Among authors: mannion j. Sci Immunol. 2022 Jun 3;7(72):eabn0175. doi: 10.1126/sciimmunol.abn0175. Epub 2022 Jun 3. Sci Immunol. 2022. PMID: 35658010 Free PMC article.
Novel biochemical, structural, and systems insights into inflammatory signaling revealed by contextual interaction proteomics.
Ciuffa R, Uliana F, Mannion J, Mehnert M, Tenev T, Marulli C, Satanowski A, Keller LML, Rodilla Ramírez PN, Ori A, Gstaiger M, Meier P, Aebersold R. Ciuffa R, et al. Among authors: mannion j. Proc Natl Acad Sci U S A. 2022 Oct 4;119(40):e2117175119. doi: 10.1073/pnas.2117175119. Epub 2022 Sep 30. Proc Natl Acad Sci U S A. 2022. PMID: 36179048 Free PMC article.
Mef2d potentiates type-2 immune responses and allergic lung inflammation.
Szeto ACH, Clark PA, Ferreira ACF, Heycock M, Griffiths EL, Jou E, Mannion J, Luan SL, Storrar S, Knolle MD, Kozik P, Jolin HE, Fallon PG, McKenzie ANJ. Szeto ACH, et al. Among authors: mannion j. Science. 2024 Jun 28;384(6703):eadl0370. doi: 10.1126/science.adl0370. Epub 2024 Jun 28. Science. 2024. PMID: 38935708 Free PMC article.
An ultra-conserved poison exon in the Tra2b gene encoding a splicing activator is essential for male fertility and meiotic cell division.
Dalgliesh C, Aldalaqan S, Atallah C, Best A, Scott E, Ehrmann I, Merces G, Mannion J, Badurova B, Sandher R, Illing Y, Wirth B, Wells S, Codner G, Teboul L, Smith GR, Hedley A, Herbert M, de Rooij DG, Miles C, Reynard LN, Elliott DJ. Dalgliesh C, et al. Among authors: mannion j. EMBO J. 2025 Jan 2. doi: 10.1038/s44318-024-00344-6. Online ahead of print. EMBO J. 2025. PMID: 39748121 Free article.
Unresponsive patient with bradycardia.
Mannion J, Murray C, Wilkinson M. Mannion J, et al. Heart. 2024 Dec 13;111(1):17-44. doi: 10.1136/heartjnl-2024-324688. Heart. 2024. PMID: 39674589 No abstract available.
135 results