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Valproic acid targets IDH1 mutants through alteration of lipid metabolism.
Elahi LS, Condro MC, Kawaguchi R, Qin Y, Alvarado AG, Gruender B, Qi H, Li T, Lai A, Castro MG, Lowenstein PR, Garrett MC, Kornblum HI. Elahi LS, et al. NPJ Metab Health Dis. 2024;2(1):20. doi: 10.1038/s44324-024-00021-6. Epub 2024 Aug 13. NPJ Metab Health Dis. 2024. PMID: 39149696 Free PMC article.
HDAC1 and HDAC6 are essential for driving growth in IDH1 mutant glioma.
Garrett MC, Albano R, Carnwath T, Elahi L, Behrmann CA, Pemberton M, Woo D, O'Brien E, VanCauwenbergh B, Perentesis J, Shah S, Hagan M, Kendler A, Zhao C, Paranjpe A, Roskin K, Kornblum H, Plas DR, Lu QR. Garrett MC, et al. Among authors: elahi l. Sci Rep. 2023 Aug 1;13(1):12433. doi: 10.1038/s41598-023-33889-3. Sci Rep. 2023. PMID: 37528157 Free PMC article.
Low- and high-grade glioma endothelial cells differentially regulate tumor growth.
Muthukrishnan SD, Qi H, Wang D, Elahi L, Pham A, Alvarado AG, Li T, Gao F, Kawaguchi R, Lai A, Kornblum HI. Muthukrishnan SD, et al. Among authors: elahi l. bioRxiv [Preprint]. 2023 Jul 7:2023.07.07.548125. doi: 10.1101/2023.07.07.548125. bioRxiv. 2023. Update in: Mol Cancer Res. 2024 Jul 2;22(7):656-667. doi: 10.1158/1541-7786.MCR-23-1069 PMID: 37461434 Free PMC article. Updated. Preprint.
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