Ince I - Search Results

1

Model-informed bridging of rivaroxaban doses for thromboprophylaxis in pediatric patients aged 9 years and older with congenital heart disease.

Willmann S, Ince I, Ahsman M, Coboeken K, Zhang Y, Thelen K, Kubitza D, Zannikos P, Zhou W, Pina LM, Post T, Lippert J. Willmann S, et al. Among authors: ince i. CPT Pharmacometrics Syst Pharmacol. 2022 Aug;11(8):1111-1121. doi: 10.1002/psp4.12830. Epub 2022 Jun 14. CPT Pharmacometrics Syst Pharmacol. 2022. PMID: 35665486 Free PMC article.

2

Evaluation of changes in oral drug absorption in preterm and term neonates for Biopharmaceutics Classification System (BCS) class I and II compounds.

Somani AA, Thelen K, Zheng S, Trame MN, Coboeken K, Meyer M, Schnizler K, Ince I, Willmann S, Schmidt S. Somani AA, et al. Among authors: ince i. Br J Clin Pharmacol. 2016 Jan;81(1):137-47. doi: 10.1111/bcp.12752. Epub 2015 Oct 30. Br J Clin Pharmacol. 2016. PMID: 26302359 Free PMC article.

3

Physiologically Based Pharmacokinetic Modeling of Renally Cleared Drugs in Pregnant Women.

Dallmann A, Ince I, Solodenko J, Meyer M, Willmann S, Eissing T, Hempel G. Dallmann A, et al. Among authors: ince i. Clin Pharmacokinet. 2017 Dec;56(12):1525-1541. doi: 10.1007/s40262-017-0538-0. Clin Pharmacokinet. 2017. PMID: 28391404

4

Gestation-Specific Changes in the Anatomy and Physiology of Healthy Pregnant Women: An Extended Repository of Model Parameters for Physiologically Based Pharmacokinetic Modeling in Pregnancy.

Dallmann A, Ince I, Meyer M, Willmann S, Eissing T, Hempel G. Dallmann A, et al. Among authors: ince i. Clin Pharmacokinet. 2017 Nov;56(11):1303-1330. doi: 10.1007/s40262-017-0539-z. Clin Pharmacokinet. 2017. PMID: 28401479 Review.

5

A Physiologically Based Pharmacokinetic Model for Pregnant Women to Predict the Pharmacokinetics of Drugs Metabolized Via Several Enzymatic Pathways.

Dallmann A, Ince I, Coboeken K, Eissing T, Hempel G. Dallmann A, et al. Among authors: ince i. Clin Pharmacokinet. 2018 Jun;57(6):749-768. doi: 10.1007/s40262-017-0594-5. Clin Pharmacokinet. 2018. PMID: 28924743

6

Applied Concepts in PBPK Modeling: How to Extend an Open Systems Pharmacology Model to the Special Population of Pregnant Women.

Dallmann A, Solodenko J, Ince I, Eissing T. Dallmann A, et al. Among authors: ince i. CPT Pharmacometrics Syst Pharmacol. 2018 Jul;7(7):419-431. doi: 10.1002/psp4.12300. Epub 2018 Apr 20. CPT Pharmacometrics Syst Pharmacol. 2018. PMID: 29569837 Free PMC article.

7

Predictive Pediatric Modeling and Simulation Using Ontogeny Information.

Ince I, Solodenko J, Frechen S, Dallmann A, Niederalt C, Schlender J, Burghaus R, Lippert J, Willmann S. Ince I, et al. J Clin Pharmacol. 2019 Sep;59 Suppl 1:S95-S103. doi: 10.1002/jcph.1497. J Clin Pharmacol. 2019. PMID: 31502689 Review.

8

A generic framework for the physiologically-based pharmacokinetic platform qualification of PK-Sim and its application to predicting cytochrome P450 3A4-mediated drug-drug interactions.

Frechen S, Solodenko J, Wendl T, Dallmann A, Ince I, Lehr T, Lippert J, Burghaus R. Frechen S, et al. Among authors: ince i. CPT Pharmacometrics Syst Pharmacol. 2021 Jun;10(6):633-644. doi: 10.1002/psp4.12636. Epub 2021 May 24. CPT Pharmacometrics Syst Pharmacol. 2021. PMID: 33946131 Free PMC article.

9

Predictive Performance of Physiology-Based Pharmacokinetic Dose Estimates for Pediatric Trials: Evaluation With 10 Bayer Small-Molecule Compounds in Children.

Ince I, Dallmann A, Frechen S, Coboeken K, Niederalt C, Wendl T, Block M, Meyer M, Eissing T, Burghaus R, Lippert J, Willmann S, Schlender JF. Ince I, et al. J Clin Pharmacol. 2021 Jun;61 Suppl 1(Suppl 1):S70-S82. doi: 10.1002/jcph.1869. J Clin Pharmacol. 2021. PMID: 34185905 Free PMC article.

10

Clinical investigation of the biopharmaceutical characteristics of nifurtimox tablets - Implications for quality control and application.

Stass H, Just S, Weimann B, Ince I, Willmann S, Feleder E, Freitas C, Yerino G, Münster U. Stass H, et al. Among authors: ince i. Eur J Pharm Sci. 2021 Nov 1;166:105940. doi: 10.1016/j.ejps.2021.105940. Epub 2021 Jul 12. Eur J Pharm Sci. 2021. PMID: 34265407 Free article.

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