Barquist L - Search Results

1

A target expression threshold dictates invader defense and prevents autoimmunity by CRISPR-Cas13.

Vialetto E, Yu Y, Collins SP, Wandera KG, Barquist L, Beisel CL. Vialetto E, et al. Among authors: barquist l. Cell Host Microbe. 2022 Aug 10;30(8):1151-1162.e6. doi: 10.1016/j.chom.2022.05.013. Epub 2022 Jun 10. Cell Host Microbe. 2022. PMID: 35690065 Free PMC article.

2

Noncanonical crRNAs derived from host transcripts enable multiplexable RNA detection by Cas9.

Jiao C, Sharma S, Dugar G, Peeck NL, Bischler T, Wimmer F, Yu Y, Barquist L, Schoen C, Kurzai O, Sharma CM, Beisel CL. Jiao C, et al. Among authors: barquist l. Science. 2021 May 28;372(6545):941-948. doi: 10.1126/science.abe7106. Epub 2021 Apr 27. Science. 2021. PMID: 33906967 Free PMC article.

3

Improved prediction of bacterial CRISPRi guide efficiency from depletion screens through mixed-effect machine learning and data integration.

Yu Y, Gawlitt S, de Andrade E Sousa LB, Merdivan E, Piraud M, Beisel CL, Barquist L. Yu Y, et al. Among authors: barquist l. Genome Biol. 2024 Jan 11;25(1):13. doi: 10.1186/s13059-023-03153-y. Genome Biol. 2024. PMID: 38200565 Free PMC article.

4

Expanding the flexibility of base editing for high-throughput genetic screens in bacteria.

Gawlitt S, Collins SP, Yu Y, Blackman SA, Barquist L, Beisel CL. Gawlitt S, et al. Among authors: barquist l. Nucleic Acids Res. 2024 Apr 24;52(7):4079-4097. doi: 10.1093/nar/gkae174. Nucleic Acids Res. 2024. PMID: 38499498 Free PMC article.

5

Systematic interrogation of CRISPR antimicrobials in Klebsiella pneumoniae reveals nuclease-, guide- and strain-dependent features influencing antimicrobial activity.

Vialetto E, Miele S, Goren MG, Yu J, Yu Y, Collias D, Beamud B, Osbelt L, Lourenço M, Strowig T, Brisse S, Barquist L, Qimron U, Bikard D, Beisel CL. Vialetto E, et al. Among authors: barquist l. Nucleic Acids Res. 2024 Jun 10;52(10):6079-6091. doi: 10.1093/nar/gkae281. Nucleic Acids Res. 2024. PMID: 38661215 Free PMC article.

6

Global Maps of ProQ Binding In Vivo Reveal Target Recognition via RNA Structure and Stability Control at mRNA 3' Ends.

Holmqvist E, Li L, Bischler T, Barquist L, Vogel J. Holmqvist E, et al. Among authors: barquist l. Mol Cell. 2018 Jun 7;70(5):971-982.e6. doi: 10.1016/j.molcel.2018.04.017. Epub 2018 May 24. Mol Cell. 2018. PMID: 29804828 Free article.

7

The minimal meningococcal ProQ protein has an intrinsic capacity for structure-based global RNA recognition.

Bauriedl S, Gerovac M, Heidrich N, Bischler T, Barquist L, Vogel J, Schoen C. Bauriedl S, et al. Among authors: barquist l. Nat Commun. 2020 Jun 4;11(1):2823. doi: 10.1038/s41467-020-16650-6. Nat Commun. 2020. PMID: 32499480 Free PMC article.

8

Global RNA profiles show target selectivity and physiological effects of peptide-delivered antisense antibiotics.

Popella L, Jung J, Popova K, Ðurica-Mitić S, Barquist L, Vogel J. Popella L, et al. Among authors: barquist l. Nucleic Acids Res. 2021 May 7;49(8):4705-4724. doi: 10.1093/nar/gkab242. Nucleic Acids Res. 2021. PMID: 33849070 Free PMC article.

9

Global identification of RsmA/N binding sites in Pseudomonas aeruginosa by in vivo UV CLIP-seq.

Chihara K, Barquist L, Takasugi K, Noda N, Tsuneda S. Chihara K, et al. Among authors: barquist l. RNA Biol. 2021 Dec;18(12):2401-2416. doi: 10.1080/15476286.2021.1917184. Epub 2021 Apr 27. RNA Biol. 2021. PMID: 33866926 Free PMC article.

10

Comprehensive analysis of PNA-based antisense antibiotics targeting various essential genes in uropathogenic Escherichia coli.

Popella L, Jung J, Do PT, Hayward RJ, Barquist L, Vogel J. Popella L, et al. Among authors: barquist l. Nucleic Acids Res. 2022 Jun 24;50(11):6435-6452. doi: 10.1093/nar/gkac362. Nucleic Acids Res. 2022. PMID: 35687096 Free PMC article.

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