Lorenz K - Search Results

1

Raf Kinase Inhibitory Protein regulates the cAMP-dependent protein kinase signaling pathway through a positive feedback loop.

Lee J, Olivieri C, Ong C, Masterson LR, Gomes S, Lee BS, Schaefer F, Lorenz K, Veglia G, Rosner MR. Lee J, et al. Among authors: lorenz k. Proc Natl Acad Sci U S A. 2022 Jun 21;119(25):e2121867119. doi: 10.1073/pnas.2121867119. Epub 2022 Jun 13. Proc Natl Acad Sci U S A. 2022. PMID: 35696587 Free PMC article.

2

Protein kinase C switches the Raf kinase inhibitor from Raf-1 to GRK-2.

Lorenz K, Lohse MJ, Quitterer U. Lorenz K, et al. Nature. 2003 Dec 4;426(6966):574-9. doi: 10.1038/nature02158. Nature. 2003. PMID: 14654844

3

Interference with ERK(Thr188) phosphorylation impairs pathological but not physiological cardiac hypertrophy.

Ruppert C, Deiss K, Herrmann S, Vidal M, Oezkur M, Gorski A, Weidemann F, Lohse MJ, Lorenz K. Ruppert C, et al. Among authors: lorenz k. Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):7440-5. doi: 10.1073/pnas.1221999110. Epub 2013 Apr 15. Proc Natl Acad Sci U S A. 2013. PMID: 23589880 Free PMC article.

4

Raf kinase inhibitor protein: lessons of a better way for β-adrenergic receptor activation in the heart.

Lorenz K, Rosner MR, Brand T, Schmitt JP. Lorenz K, et al. J Physiol. 2017 Jun 15;595(12):4073-4087. doi: 10.1113/JP274064. Epub 2017 May 23. J Physiol. 2017. PMID: 28444807 Free PMC article. Review.

5

Conserved salt-bridge competition triggered by phosphorylation regulates the protein interactome.

Skinner JJ, Wang S, Lee J, Ong C, Sommese R, Sivaramakrishnan S, Koelmel W, Hirschbeck M, Schindelin H, Kisker C, Lorenz K, Sosnick TR, Rosner MR. Skinner JJ, et al. Among authors: lorenz k. Proc Natl Acad Sci U S A. 2017 Dec 19;114(51):13453-13458. doi: 10.1073/pnas.1711543114. Epub 2017 Dec 5. Proc Natl Acad Sci U S A. 2017. PMID: 29208709 Free PMC article.

6

Harnessing RKIP to Combat Heart Disease and Cancer.

Lorenz K, Rosner MR. Lorenz K, et al. Cancers (Basel). 2022 Feb 9;14(4):867. doi: 10.3390/cancers14040867. Cancers (Basel). 2022. PMID: 35205615 Free PMC article. Review.

7

The amino-terminal domain of G-protein-coupled receptor kinase 2 is a regulatory Gbeta gamma binding site.

Eichmann T, Lorenz K, Hoffmann M, Brockmann J, Krasel C, Lohse MJ, Quitterer U. Eichmann T, et al. Among authors: lorenz k. J Biol Chem. 2003 Mar 7;278(10):8052-7. doi: 10.1074/jbc.M204795200. Epub 2002 Dec 16. J Biol Chem. 2003. PMID: 12486133 Free article.

8

Beta-arrestin binding to the beta2-adrenergic receptor requires both receptor phosphorylation and receptor activation.

Krasel C, Bünemann M, Lorenz K, Lohse MJ. Krasel C, et al. Among authors: lorenz k. J Biol Chem. 2005 Mar 11;280(10):9528-35. doi: 10.1074/jbc.M413078200. Epub 2005 Jan 5. J Biol Chem. 2005. PMID: 15634674 Free article.

9

Cardiac hypertrophy: targeting Raf/MEK/ERK1/2-signaling.

Lorenz K, Schmitt JP, Vidal M, Lohse MJ. Lorenz K, et al. Int J Biochem Cell Biol. 2009 Dec;41(12):2351-5. doi: 10.1016/j.biocel.2009.08.002. Epub 2009 Aug 8. Int J Biochem Cell Biol. 2009. PMID: 19666137 Review.

10

Raf kinase inhibitor protein (RKIP) dimer formation controls its target switch from Raf1 to G protein-coupled receptor kinase (GRK) 2.

Deiss K, Kisker C, Lohse MJ, Lorenz K. Deiss K, et al. Among authors: lorenz k. J Biol Chem. 2012 Jul 6;287(28):23407-17. doi: 10.1074/jbc.M112.363812. Epub 2012 May 17. J Biol Chem. 2012. PMID: 22610096 Free PMC article.

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