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Application of the adverse outcome pathway concept for investigating developmental neurotoxicity potential of Chinese herbal medicines by using human neural progenitor cells in vitro.
Klose J, Li L, Pahl M, Bendt F, Hübenthal U, Jüngst C, Petzsch P, Schauss A, Köhrer K, Leung PC, Wang CC, Koch K, Tigges J, Fan X, Fritsche E. Klose J, et al. Among authors: hubenthal u. Cell Biol Toxicol. 2023 Feb;39(1):319-343. doi: 10.1007/s10565-022-09730-4. Epub 2022 Jun 15. Cell Biol Toxicol. 2023. PMID: 35701726 Free PMC article.
Xenobiotic metabolism capacities of human skin in comparison with a 3D-epidermis model and keratinocyte-based cell culture as in vitro alternatives for chemical testing: phase II enzymes.
Götz C, Pfeiffer R, Tigges J, Ruwiedel K, Hübenthal U, Merk HF, Krutmann J, Edwards RJ, Abel J, Pease C, Goebel C, Hewitt N, Fritsche E. Götz C, et al. Among authors: hubenthal u. Exp Dermatol. 2012 May;21(5):364-9. doi: 10.1111/j.1600-0625.2012.01478.x. Exp Dermatol. 2012. PMID: 22509834
The new aryl hydrocarbon receptor antagonist E/Z-2-benzylindene-5,6-dimethoxy-3,3-dimethylindan-1-one protects against UVB-induced signal transduction.
Tigges J, Haarmann-Stemmann T, Vogel CFA, Grindel A, Hübenthal U, Brenden H, Grether-Beck S, Vielhaber G, Johncock W, Krutmann J, Fritsche E. Tigges J, et al. Among authors: hubenthal u. J Invest Dermatol. 2014 Feb;134(2):556-559. doi: 10.1038/jid.2013.362. Epub 2013 Aug 30. J Invest Dermatol. 2014. PMID: 23995519 Free PMC article. No abstract available.
A transcriptome comparison of time-matched developing human, mouse and rat neural progenitor cells reveals human uniqueness.
Masjosthusmann S, Becker D, Petzuch B, Klose J, Siebert C, Deenen R, Barenys M, Baumann J, Dach K, Tigges J, Hübenthal U, Köhrer K, Fritsche E. Masjosthusmann S, et al. Among authors: hubenthal u. Toxicol Appl Pharmacol. 2018 Sep 1;354:40-55. doi: 10.1016/j.taap.2018.05.009. Epub 2018 May 9. Toxicol Appl Pharmacol. 2018. PMID: 29753005
Characterization and application of electrically active neuronal networks established from human induced pluripotent stem cell-derived neural progenitor cells for neurotoxicity evaluation.
Nimtz L, Hartmann J, Tigges J, Masjosthusmann S, Schmuck M, Keßel E, Theiss S, Köhrer K, Petzsch P, Adjaye J, Wigmann C, Wieczorek D, Hildebrandt B, Bendt F, Hübenthal U, Brockerhoff G, Fritsche E. Nimtz L, et al. Among authors: hubenthal u. Stem Cell Res. 2020 May;45:101761. doi: 10.1016/j.scr.2020.101761. Epub 2020 Mar 10. Stem Cell Res. 2020. PMID: 32244191 Free article.
15 results