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Caspase-7 activates ASM to repair gasdermin and perforin pores.
Nozaki K, Maltez VI, Rayamajhi M, Tubbs AL, Mitchell JE, Lacey CA, Harvest CK, Li L, Nash WT, Larson HN, McGlaughon BD, Moorman NJ, Brown MG, Whitmire JK, Miao EA. Nozaki K, et al. Among authors: moorman nj. Nature. 2022 Jun;606(7916):960-967. doi: 10.1038/s41586-022-04825-8. Epub 2022 Jun 15. Nature. 2022. PMID: 35705808 Free PMC article.
Structure Activity of β-Amidomethyl Vinyl Sulfones as Covalent Inhibitors of Chikungunya nsP2 Cysteine Protease with Anti-alphavirus Activity.
Ghoshal A, Asressu KH, Hossain MA, Brown PJ, Merten EM, Sears JD, Perveen S, Pearce KH, Popov KI, Moorman NJ, Heise MT, Willson TM. Ghoshal A, et al. Among authors: moorman nj. bioRxiv [Preprint]. 2024 Jun 13:2024.06.12.598722. doi: 10.1101/2024.06.12.598722. bioRxiv. 2024. Update in: J Med Chem. 2024 Sep 26;67(18):16505-16532. doi: 10.1021/acs.jmedchem.4c01346 PMID: 38915519 Free PMC article. Updated. Preprint.
Viral and host network analysis of the human cytomegalovirus transcriptome in latency.
Collins-McMillen D, De Oliveira Pessoa D, Zarrella K, Parkins CJ, Daily M, Moorman NJ, Kamil JP, Caposio P, Padi M, Goodrum FD. Collins-McMillen D, et al. Among authors: moorman nj. bioRxiv [Preprint]. 2024 May 21:2024.05.21.594597. doi: 10.1101/2024.05.21.594597. bioRxiv. 2024. PMID: 38826434 Free PMC article. Preprint.
miniMAVS, You Complete Me!
Rayamajhi M, Miao EA, Moorman NJ. Rayamajhi M, et al. Among authors: moorman nj. Cell. 2014 Feb 13;156(4):629-30. doi: 10.1016/j.cell.2014.01.045. Cell. 2014. PMID: 24529369 Free PMC article.
NLRX1 promotes immediate IRF1-directed antiviral responses by limiting dsRNA-activated translational inhibition mediated by PKR.
Feng H, Lenarcic EM, Yamane D, Wauthier E, Mo J, Guo H, McGivern DR, González-López O, Misumi I, Reid LM, Whitmire JK, Ting JP, Duncan JA, Moorman NJ, Lemon SM. Feng H, et al. Among authors: moorman nj. Nat Immunol. 2017 Dec;18(12):1299-1309. doi: 10.1038/ni.3853. Epub 2017 Oct 2. Nat Immunol. 2017. PMID: 28967880 Free PMC article.
The ZCCHC14/TENT4 complex is required for hepatitis A virus RNA synthesis.
Li Y, Misumi I, Shiota T, Sun L, Lenarcic EM, Kim H, Shirasaki T, Hertel-Wulff A, Tibbs T, Mitchell JE, McKnight KL, Cameron CE, Moorman NJ, McGivern DR, Cullen JM, Whitmire JK, Lemon SM. Li Y, et al. Among authors: moorman nj. Proc Natl Acad Sci U S A. 2022 Jul 12;119(28):e2204511119. doi: 10.1073/pnas.2204511119. Epub 2022 Jul 7. Proc Natl Acad Sci U S A. 2022. PMID: 35867748 Free PMC article.
Precision mouse models with expanded tropism for human pathogens.
Wahl A, De C, Abad Fernandez M, Lenarcic EM, Xu Y, Cockrell AS, Cleary RA, Johnson CE, Schramm NJ, Rank LM, Newsome IG, Vincent HA, Sanders W, Aguilera-Sandoval CR, Boone A, Hildebrand WH, Dayton PA, Baric RS, Pickles RJ, Braunstein M, Moorman NJ, Goonetilleke N, Victor Garcia J. Wahl A, et al. Among authors: moorman nj. Nat Biotechnol. 2019 Oct;37(10):1163-1173. doi: 10.1038/s41587-019-0225-9. Epub 2019 Aug 26. Nat Biotechnol. 2019. PMID: 31451733 Free PMC article.
110 results