Nafie MS - Search Results

1

Novel bis-amide-based bis-thiazoles as Anti-colorectal Cancer Agents Through Bcl-2 Inhibition: Synthesis, In Vitro, and In Vivo studies.

Dawood KM, Raslan MA, Abbas AA, Mohamed BE, Nafie MS. Dawood KM, et al. Among authors: nafie ms. Anticancer Agents Med Chem. 2023;23(3):328-345. doi: 10.2174/1871520622666220615140239. Anticancer Agents Med Chem. 2023. PMID: 35708084

2

Discovery of novel pyrazolo[3,4-b]pyridine scaffold-based derivatives as potential PIM-1 kinase inhibitors in breast cancer MCF-7 cells.

Nafie MS, Amer AM, Mohamed AK, Tantawy ES. Nafie MS, et al. Bioorg Med Chem. 2020 Dec 15;28(24):115828. doi: 10.1016/j.bmc.2020.115828. Epub 2020 Nov 2. Bioorg Med Chem. 2020. PMID: 33166925

3

Synthesis of new substituted pyridine derivatives as potent anti-liver cancer agents through apoptosis induction: In vitro, in vivo, and in silico integrated approaches.

Boraei ATA, Eltamany EH, Ali IAI, Gebriel SM, Nafie MS. Boraei ATA, et al. Among authors: nafie ms. Bioorg Chem. 2021 Jun;111:104877. doi: 10.1016/j.bioorg.2021.104877. Epub 2021 Mar 29. Bioorg Chem. 2021. PMID: 33839579

4

Design, synthesis and evaluation of new quinazolin-4-one derivatives as apoptotic enhancers and autophagy inhibitors with potent antitumor activity.

ElZahabi HSA, Nafie MS, Osman D, Elghazawy NH, Soliman DH, El-Helby AAH, Arafa RK. ElZahabi HSA, et al. Among authors: nafie ms. Eur J Med Chem. 2021 Oct 15;222:113609. doi: 10.1016/j.ejmech.2021.113609. Epub 2021 Jun 5. Eur J Med Chem. 2021. PMID: 34119830

5

Novel Bis-Thiazole Derivatives: Synthesis and Potential Cytotoxic Activity Through Apoptosis With Molecular Docking Approaches.

Dawood KM, Raslan MA, Abbas AA, Mohamed BE, Abdellattif MH, Nafie MS, Hassan MK. Dawood KM, et al. Among authors: nafie ms. Front Chem. 2021 Aug 12;9:694870. doi: 10.3389/fchem.2021.694870. eCollection 2021. Front Chem. 2021. PMID: 34458233 Free PMC article.

6

Topo II inhibition and DNA intercalation by new phthalazine-based derivatives as potent anticancer agents: design, synthesis, anti-proliferative, docking, and in vivo studies.

Khalifa MM, Al-Karmalawy AA, Elkaeed EB, Nafie MS, Tantawy MA, Eissa IH, Mahdy HA. Khalifa MM, et al. Among authors: nafie ms. J Enzyme Inhib Med Chem. 2022 Dec;37(1):299-314. doi: 10.1080/14756366.2021.2007905. J Enzyme Inhib Med Chem. 2022. PMID: 34894955 Free PMC article.

7

Design and synthesis of new bis(1,2,4-triazolo[3,4-b][1,3,4]thiadiazines) and bis((quinoxalin-2-yl)phenoxy)alkanes as anti-breast cancer agents through dual PARP-1 and EGFR targets inhibition.

Thabet FM, Dawood KM, Ragab EA, Nafie MS, Abbas AA. Thabet FM, et al. Among authors: nafie ms. RSC Adv. 2022 Aug 19;12(36):23644-23660. doi: 10.1039/d2ra03549a. eCollection 2022 Aug 16. RSC Adv. 2022. PMID: 36090415 Free PMC article.

8

Rational Design, Synthesis and Biological Evaluation of Novel Pyrazoline-Based Antiproliferative Agents in MCF-7 Cancer Cells.

Fakhry MM, Mahmoud K, Nafie MS, Noor AO, Hareeri RH, Salama I, Kishk SM. Fakhry MM, et al. Among authors: nafie ms. Pharmaceuticals (Basel). 2022 Oct 10;15(10):1245. doi: 10.3390/ph15101245. Pharmaceuticals (Basel). 2022. PMID: 36297358 Free PMC article.

9

Ligand-Based Design on the Dog-Bone-Shaped BIBR1532 Pharmacophoric Features and Synthesis of Novel Analogues as Promising Telomerase Inhibitors with In Vitro and In Vivo Evaluations.

Al-Karmalawy AA, Nafie MS, Shaldam MA, Elmaaty AA, Antar SA, El-Hamaky AA, Saleh MA, Elkamhawy A, Tawfik HO. Al-Karmalawy AA, et al. Among authors: nafie ms. J Med Chem. 2023 Jan 12;66(1):777-792. doi: 10.1021/acs.jmedchem.2c01668. Epub 2022 Dec 16. J Med Chem. 2023. PMID: 36525642

10

Discovery of PIM-1 kinase inhibitors based on the 2,5-disubstituted 1,3,4-oxadiazole scaffold against prostate cancer: Design, synthesis, in vitro and in vivo cytotoxicity investigation.

Castanet AS, Nafie MS, Said SA, Arafa RK. Castanet AS, et al. Among authors: nafie ms. Eur J Med Chem. 2023 Mar 15;250:115220. doi: 10.1016/j.ejmech.2023.115220. Epub 2023 Feb 23. Eur J Med Chem. 2023. PMID: 36848846

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