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834 results

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Page 1
Transcriptional Plasticity Drives Leukemia Immune Escape.
Eagle K, Harada T, Kalfon J, Perez MW, Heshmati Y, Ewers J, Koren JV, Dempster JM, Kugener G, Paralkar VR, Lin CY, Dharia NV, Stegmaier K, Orkin SH, Pimkin M. Eagle K, et al. Blood Cancer Discov. 2022 Sep 6;3(5):394-409. doi: 10.1158/2643-3230.BCD-21-0207. Blood Cancer Discov. 2022. PMID: 35709529 Free PMC article.
An oncogenic enhancer encodes selective selenium dependency in AML.
Eagle K, Jiang Y, Shi X, Li M, Obholzer NP, Hu T, Perez MW, Koren JV, Kitano A, Yi JS, Lin CY, Nakada D. Eagle K, et al. Cell Stem Cell. 2022 Mar 3;29(3):386-399.e7. doi: 10.1016/j.stem.2022.01.003. Epub 2022 Feb 1. Cell Stem Cell. 2022. PMID: 35108519 Free PMC article.
A distinct core regulatory module enforces oncogene expression in KMT2A-rearranged leukemia.
Harada T, Heshmati Y, Kalfon J, Perez MW, Xavier Ferrucio J, Ewers J, Hubbell Engler B, Kossenkov A, Ellegast JM, Yi JS, Bowker A, Zhu Q, Eagle K, Liu T, Kai Y, Dempster JM, Kugener G, Wickramasinghe J, Herbert ZT, Li CH, Vrabič Koren J, Weinstock DM, Paralkar VR, Nabet B, Lin CY, Dharia NV, Stegmaier K, Orkin SH, Pimkin M. Harada T, et al. Among authors: eagle k. Genes Dev. 2022 Mar 1;36(5-6):368-389. doi: 10.1101/gad.349284.121. Epub 2022 Mar 17. Genes Dev. 2022. PMID: 35301220 Free PMC article.
An oncogenic enhancer encodes selective selenium dependency in AML.
Eagle K, Jiang Y, Shi X, Li M, Obholzer ND, Hu T, Perez MW, Koren JV, Kitano A, Yi JS, Lin CY, Nakada D. Eagle K, et al. Cell Stem Cell. 2022 Apr 7;29(4):650. doi: 10.1016/j.stem.2022.03.006. Cell Stem Cell. 2022. PMID: 35395189 Free PMC article. No abstract available.
Leukemia core transcriptional circuitry is a sparsely interconnected hierarchy stabilized by incoherent feed-forward loops.
Harada T, Kalfon J, Perez MW, Eagle K, Braes FD, Batley R, Heshmati Y, Ferrucio JX, Ewers J, Mehta S, Kossenkov A, Ellegast JM, Bowker A, Wickramasinghe J, Nabet B, Paralkar VR, Dharia NV, Stegmaier K, Orkin SH, Pimkin M. Harada T, et al. Among authors: eagle k. bioRxiv [Preprint]. 2023 Mar 15:2023.03.13.532438. doi: 10.1101/2023.03.13.532438. bioRxiv. 2023. PMID: 36993171 Free PMC article. Preprint.
MYC Induces Oncogenic Stress through RNA Decay and Ribonucleotide Catabolism in Breast Cancer.
Meena JK, Wang JH, Neill NJ, Keough D, Putluri N, Katsonis P, Koire AM, Lee H, Bowling EA, Tyagi S, Orellana M, Dominguez-Vidaña R, Li H, Eagle K, Danan C, Chung HC, Yang AD, Wu W, Kurley SJ, Ho BM, Zoeller JR, Olson CM, Meerbrey KL, Lichtarge O, Sreekumar A, Dacso CC, Guddat LW, Rejman D, Hocková D, Janeba Z, Simon LM, Lin CY, Pillon MC, Westbrook TF. Meena JK, et al. Among authors: eagle k. Cancer Discov. 2024 Sep 4;14(9):1699-1716. doi: 10.1158/2159-8290.CD-22-0649. Cancer Discov. 2024. PMID: 39193992 Free PMC article.
834 results