Barran PE - Search Results

1

Novel Allosteric Mechanism of Dual p53/MDM2 and p53/MDM4 Inhibition by a Small Molecule.

Grinkevich VV, Vema A, Fawkner K, Issaeva N, Andreotti V, Dickinson ER, Hedström E, Spinnler C, Inga A, Larsson LG, Karlén A, Wilhelm M, Barran PE, Okorokov AL, Selivanova G, Zawacka-Pankau JE. Grinkevich VV, et al. Among authors: barran pe. Front Mol Biosci. 2022 Jun 1;9:823195. doi: 10.3389/fmolb.2022.823195. eCollection 2022. Front Mol Biosci. 2022. PMID: 35720128 Free PMC article.

2

Insights into the conformations of three structurally diverse proteins: cytochrome c, p53, and MDM2, provided by variable-temperature ion mobility mass spectrometry.

Dickinson ER, Jurneczko E, Pacholarz KJ, Clarke DJ, Reeves M, Ball KL, Hupp T, Campopiano D, Nikolova PV, Barran PE. Dickinson ER, et al. Among authors: barran pe. Anal Chem. 2015 Mar 17;87(6):3231-8. doi: 10.1021/ac503720v. Epub 2015 Feb 25. Anal Chem. 2015. PMID: 25629302

3

The use of ion mobility mass spectrometry to probe modulation of the structure of p53 and of MDM2 by small molecule inhibitors.

Dickinson ER, Jurneczko E, Nicholson J, Hupp TR, Zawacka-Pankau J, Selivanova G, Barran PE. Dickinson ER, et al. Among authors: barran pe. Front Mol Biosci. 2015 Jul 10;2:39. doi: 10.3389/fmolb.2015.00039. eCollection 2015. Front Mol Biosci. 2015. PMID: 26217671 Free PMC article.

4

Consequences of point mutations in melanoma-associated antigen 4 (MAGE-A4) protein: Insights from structural and biophysical studies.

Hagiwara Y, Sieverling L, Hanif F, Anton J, Dickinson ER, Bui TT, Andreeva A, Barran PE, Cota E, Nikolova PV. Hagiwara Y, et al. Among authors: barran pe. Sci Rep. 2016 Apr 28;6:25182. doi: 10.1038/srep25182. Sci Rep. 2016. PMID: 27121989 Free PMC article.

5

Structure-activity relationships in defensin dimers: a novel link between beta-defensin tertiary structure and antimicrobial activity.

Campopiano DJ, Clarke DJ, Polfer NC, Barran PE, Langley RJ, Govan JR, Maxwell A, Dorin JR. Campopiano DJ, et al. Among authors: barran pe. J Biol Chem. 2004 Nov 19;279(47):48671-9. doi: 10.1074/jbc.M404690200. Epub 2004 Aug 17. J Biol Chem. 2004. PMID: 15317821 Free article.

6

Conformation of glycosaminoglycans by ion mobility mass spectrometry and molecular modelling.

Jin L, Barran PE, Deakin JA, Lyon M, Uhrín D. Jin L, et al. Among authors: barran pe. Phys Chem Chem Phys. 2005 Oct 7;7(19):3464-71. doi: 10.1039/b508644b. Epub 2005 Aug 22. Phys Chem Chem Phys. 2005. PMID: 16273147

7

Covalent dimer species of beta-defensin Defr1 display potent antimicrobial activity against multidrug-resistant bacterial pathogens.

Taylor K, McCullough B, Clarke DJ, Langley RJ, Pechenick T, Hill A, Campopiano DJ, Barran PE, Dorin JR, Govan JR. Taylor K, et al. Among authors: barran pe. Antimicrob Agents Chemother. 2007 May;51(5):1719-24. doi: 10.1128/AAC.01531-06. Epub 2007 Mar 12. Antimicrob Agents Chemother. 2007. PMID: 17353239 Free PMC article.

8

Analysis and separation of residues important for the chemoattractant and antimicrobial activities of beta-defensin 3.

Taylor K, Clarke DJ, McCullough B, Chin W, Seo E, Yang D, Oppenheim J, Uhrin D, Govan JR, Campopiano DJ, MacMillan D, Barran P, Dorin JR. Taylor K, et al. J Biol Chem. 2008 Mar 14;283(11):6631-9. doi: 10.1074/jbc.M709238200. Epub 2008 Jan 7. J Biol Chem. 2008. PMID: 18180295 Free article.

9

Development of an ion mobility quadrupole time of flight mass spectrometer.

McCullough BJ, Kalapothakis J, Eastwood H, Kemper P, MacMillan D, Taylor K, Dorin J, Barran PE. McCullough BJ, et al. Among authors: barran pe. Anal Chem. 2008 Aug 15;80(16):6336-44. doi: 10.1021/ac800651b. Epub 2008 Jul 15. Anal Chem. 2008. PMID: 18627133

10

Isoleucine/leucine2 is essential for chemoattractant activity of beta-defensin Defb14 through chemokine receptor 6.

Tyrrell C, De Cecco M, Reynolds NL, Kilanowski F, Campopiano D, Barran P, Macmillan D, Dorin JR. Tyrrell C, et al. Mol Immunol. 2010 Mar;47(6):1378-82. doi: 10.1016/j.molimm.2009.11.025. Mol Immunol. 2010. PMID: 20022113

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