Wilhelm M - Search Results

1

Novel Allosteric Mechanism of Dual p53/MDM2 and p53/MDM4 Inhibition by a Small Molecule.

Grinkevich VV, Vema A, Fawkner K, Issaeva N, Andreotti V, Dickinson ER, Hedström E, Spinnler C, Inga A, Larsson LG, Karlén A, Wilhelm M, Barran PE, Okorokov AL, Selivanova G, Zawacka-Pankau JE. Grinkevich VV, et al. Among authors: wilhelm m. Front Mol Biosci. 2022 Jun 1;9:823195. doi: 10.3389/fmolb.2022.823195. eCollection 2022. Front Mol Biosci. 2022. PMID: 35720128 Free PMC article.

2

JNK-NQO1 axis drives TAp73-mediated tumor suppression upon oxidative and proteasomal stress.

Kostecka A, Sznarkowska A, Meller K, Acedo P, Shi Y, Mohammad Sakil HA, Kawiak A, Lion M, Królicka A, Wilhelm M, Inga A, Zawacka-Pankau J. Kostecka A, et al. Among authors: wilhelm m. Cell Death Dis. 2014 Oct 23;5(10):e1484. doi: 10.1038/cddis.2014.408. Cell Death Dis. 2014. PMID: 25341038 Free PMC article.

3

Correction to: JNK-NQO1 axis drives TAp73-mediated tumor suppression upon oxidative and proteasomal stress.

Kostecka A, Sznarkowska A, Meller K, Acedo P, Shi Y, Sakil HAM, Kawiak A, Lion M, Królicka A, Wilhelm M, Inga A, Zawacka-Pankau J. Kostecka A, et al. Among authors: wilhelm m. Cell Death Dis. 2018 Jun 7;9(6):690. doi: 10.1038/s41419-018-0654-2. Cell Death Dis. 2018. PMID: 29880796 Free PMC article.

4

Regulation of tumor suppressor p53 at the RNA level.

Vilborg A, Wilhelm MT, Wiman KG. Vilborg A, et al. J Mol Med (Berl). 2010 Jul;88(7):645-52. doi: 10.1007/s00109-010-0609-2. Epub 2010 Mar 21. J Mol Med (Berl). 2010. PMID: 20306257 Review.

5

The Tumor Microenvironment of Medulloblastoma: An Intricate Multicellular Network with Therapeutic Potential.

van Bree NFHN, Wilhelm M. van Bree NFHN, et al. Among authors: wilhelm m. Cancers (Basel). 2022 Oct 13;14(20):5009. doi: 10.3390/cancers14205009. Cancers (Basel). 2022. PMID: 36291792 Free PMC article. Review.

6

The p53 target Wig-1 regulates p53 mRNA stability through an AU-rich element.

Vilborg A, Glahder JA, Wilhelm MT, Bersani C, Corcoran M, Mahmoudi S, Rosenstierne M, Grandér D, Farnebo M, Norrild B, Wiman KG. Vilborg A, et al. Among authors: wilhelm mt. Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15756-61. doi: 10.1073/pnas.0900862106. Epub 2009 Sep 1. Proc Natl Acad Sci U S A. 2009. PMID: 19805223 Free PMC article.

7

The p53-induced mouse zinc finger protein wig-1 binds double-stranded RNA with high affinity.

Méndez-Vidal C, Wilhelm MT, Hellborg F, Qian W, Wiman KG. Méndez-Vidal C, et al. Nucleic Acids Res. 2002 May 1;30(9):1991-6. doi: 10.1093/nar/30.9.1991. Nucleic Acids Res. 2002. PMID: 11972337 Free PMC article.

8

The p53 target Wig-1: a regulator of mRNA stability and stem cell fate?

Vilborg A, Bersani C, Wilhelm MT, Wiman KG. Vilborg A, et al. Among authors: wilhelm mt. Cell Death Differ. 2011 Sep;18(9):1434-40. doi: 10.1038/cdd.2011.20. Epub 2011 Mar 11. Cell Death Differ. 2011. PMID: 21394102 Free PMC article. Review.

9

High Expression of PPM1D Induces Tumors Phenotypically Similar to TP53 Loss-of-Function Mutations in Mice.

Milosevic J, Fransson S, Gulyas M, Olsen TK, Gallo-Oller G, Treis D, Elfman LHM, Wilhelm M, Martinsson T, Baryawno N, Kogner P, Johnsen JI. Milosevic J, et al. Among authors: wilhelm m. Cancers (Basel). 2021 Oct 31;13(21):5493. doi: 10.3390/cancers13215493. Cancers (Basel). 2021. PMID: 34771656 Free PMC article.

10

PRIMA-1(MET)/APR-246 targets mutant forms of p53 family members p63 and p73.

Rökaeus N, Shen J, Eckhardt I, Bykov VJ, Wiman KG, Wilhelm MT. Rökaeus N, et al. Among authors: wilhelm mt. Oncogene. 2010 Dec 9;29(49):6442-51. doi: 10.1038/onc.2010.382. Epub 2010 Sep 6. Oncogene. 2010. PMID: 20818419

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