Partridge MA - Search Results

1

Interference in a Neutralizing Antibody Assay for Odronextamab, a CD20xCD3 Bispecific mAb, from Prior Rituximab Therapy and Possible Mitigation Strategy.

Irvin SC, D'Orvilliers A, Bloch N, Boccio K, Pennucci J, Brouwer-Visser J, Ullman E, Rajadhyaksha M, Hassanein M, Potocky T, Torri A, Hermann A, Partridge MA. Irvin SC, et al. Among authors: partridge ma. AAPS J. 2022 Jun 21;24(4):76. doi: 10.1208/s12248-022-00724-y. AAPS J. 2022. PMID: 35725847

2

Drug Removal Strategies in Competitive Ligand Binding Neutralizing Antibody (NAb) Assays: Highly Drug-Tolerant Methods and Interpreting Immunogenicity Data.

Partridge MA, Karayusuf EK, Shyu G, Georgaros C, Torri A, Sumner G. Partridge MA, et al. AAPS J. 2020 Aug 17;22(5):112. doi: 10.1208/s12248-020-00497-2. AAPS J. 2020. PMID: 32808205

3

Bioanalytical Challenges due to Prior Checkpoint Inhibitor Exposure: Interference and Mitigation in Drug Concentration and Immunogenicity Assays.

Dengler AF, Weiss R, Truong T, Irvin SC, Gadhia N, Hassanein M, Georgaros C, Taylor JA, Paccaly A, Sumner G, Andisik MD, Torri A, Partridge MA. Dengler AF, et al. Among authors: partridge ma. AAPS J. 2021 Oct 4;23(6):109. doi: 10.1208/s12248-021-00643-4. AAPS J. 2021. PMID: 34608545 Free PMC article.

4

Pre-existing Reactivity to an IgG4 Fc-Epitope: Characterization and Mitigation of Interference in a Bridging Anti-drug Antibody Assay.

Partridge MA, Chen J, Karayusuf EK, Sirimanne T, Stefan C, Lai CH, Gathani M, DeStefano L, Rozanski M, McAfee S, Rajadhyaksha M, Andisik MD, Torri A, Sumner G. Partridge MA, et al. AAPS J. 2022 Jul 1;24(4):78. doi: 10.1208/s12248-022-00729-7. AAPS J. 2022. PMID: 35778641

5

Assessment of clinically relevant immunogenicity for mAbs; are we over reporting ADA?

Hassanein M, Partridge MA, Shao W, Torri A. Hassanein M, et al. Among authors: partridge ma. Bioanalysis. 2020 Sep;12(18):1325-1336. doi: 10.4155/bio-2020-0174. Epub 2020 Sep 18. Bioanalysis. 2020. PMID: 32946271

6

Isotyping and Semi-Quantitation of Monkey Anti-Drug Antibodies by Immunocapture Liquid Chromatography-Mass Spectrometry.

Huang X, Xu X, Partridge MA, Chen J, Koehler-Stec E, Sumner G, Qiu H, Torri A, Li N. Huang X, et al. Among authors: partridge ma. AAPS J. 2021 Jan 6;23(1):16. doi: 10.1208/s12248-020-00538-w. AAPS J. 2021. PMID: 33404777 Free PMC article.

7

REGEN-COV^® antibody cocktail bioanalytical strategy: comparison of LC-MRM-MS and immunoassay methods for drug quantification.

Irvin SC, Ganguly S, Weiss R, Elango C, Zhong X, Mao Y, Yan H, Li N, Sumner G, Turner KC, Davis JD, DiCioccio AT, Andisik MD, Partridge MA, Torri A. Irvin SC, et al. Among authors: partridge ma. Bioanalysis. 2021 Dec;13(24):1827-1836. doi: 10.4155/bio-2021-0190. Epub 2021 Nov 8. Bioanalysis. 2021. PMID: 34743612 Free PMC article.

8

Assay pH and critical reagent optimization in measuring concentrations of a monoclonal antibody and its target.

Chen J, Kendra K, Shank S, Rafique A, Ehrlich G, Lin KJ, DeStefano L, Andisik MD, Partridge MA, Torri A, Sumner G. Chen J, et al. Among authors: partridge ma. Bioanalysis. 2022 Apr;14(8):491-502. doi: 10.4155/bio-2021-0276. Epub 2022 Mar 17. Bioanalysis. 2022. PMID: 35297286 Free article.

9

Comparison of Titer and Signal to Noise (S/N) for Determination of Anti-drug Antibody Magnitude Using Clinical Data from an Industry Consortium.

Starcevic Manning M, Hassanein M, Partridge MA, Jawa V, Mora J, Ryman J, Barker B, Braithwaite C, Carleton K, Hay L, Hottenstein C, Kubiak RJ, Devanarayan V. Starcevic Manning M, et al. Among authors: partridge ma. AAPS J. 2022 Jul 12;24(4):81. doi: 10.1208/s12248-022-00728-8. AAPS J. 2022. PMID: 35821280

10

Matrix interference from Fc-Fc interactions in immunoassays for detecting human IgG4 therapeutics.

Partridge MA, Karayusuf EK, Dhulipala G, Dreyer R, Daly T, Sumner G, Pyles E, Torri A. Partridge MA, et al. Bioanalysis. 2015;7(20):2701-12. doi: 10.4155/bio.15.152. Epub 2015 Oct 27. Bioanalysis. 2015. PMID: 26505555

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