Southam HM - Search Results

1

CORM-3 induces DNA damage through Ru(II) binding to DNA.

Lyon RF, Southam HM, Trevitt CR, Liao C, El-Khamisy SF, Poole RK, Williamson MP. Lyon RF, et al. Among authors: southam hm. Biochem J. 2022 Jul 15;479(13):1429-1439. doi: 10.1042/BCJ20220254. Biochem J. 2022. PMID: 35726678 Free PMC article.

2

A thiol-reactive Ru(II) ion, not CO release, underlies the potent antimicrobial and cytotoxic properties of CO-releasing molecule-3.

Southam HM, Smith TW, Lyon RL, Liao C, Trevitt CR, Middlemiss LA, Cox FL, Chapman JA, El-Khamisy SF, Hippler M, Williamson MP, Henderson PJF, Poole RK. Southam HM, et al. Redox Biol. 2018 Sep;18:114-123. doi: 10.1016/j.redox.2018.06.008. Epub 2018 Jun 30. Redox Biol. 2018. PMID: 30007887 Free PMC article.

3

The Microbiology of Ruthenium Complexes.

Southam HM, Butler JA, Chapman JA, Poole RK. Southam HM, et al. Adv Microb Physiol. 2017;71:1-96. doi: 10.1016/bs.ampbs.2017.03.001. Epub 2017 May 29. Adv Microb Physiol. 2017. PMID: 28760320 Review.

4

Do nitric oxide, carbon monoxide and hydrogen sulfide really qualify as 'gasotransmitters' in bacteria?

Wareham LK, Southam HM, Poole RK. Wareham LK, et al. Among authors: southam hm. Biochem Soc Trans. 2018 Oct 19;46(5):1107-1118. doi: 10.1042/BST20170311. Epub 2018 Sep 6. Biochem Soc Trans. 2018. PMID: 30190328 Free PMC article. Review.

5

Using Nanoscopy To Probe the Biological Activity of Antimicrobial Leads That Display Potent Activity against Pathogenic, Multidrug Resistant, Gram-Negative Bacteria.

Smitten KL, Southam HM, de la Serna JB, Gill MR, Jarman PJ, Smythe CGW, Poole RK, Thomas JA. Smitten KL, et al. Among authors: southam hm. ACS Nano. 2019 May 28;13(5):5133-5146. doi: 10.1021/acsnano.8b08440. Epub 2019 Apr 9. ACS Nano. 2019. PMID: 30964642 Free article.

6

Synthesis and biological properties of tetranuclear ruthenium complexes containing the bis[4(4'-methyl-2,2'-bipyridyl)]-1,7-heptane ligand.

Sun B, Sundaraneedi MK, Southam HM, Poole RK, Musgrave IF, Keene FR, Collins JG. Sun B, et al. Among authors: southam hm. Dalton Trans. 2019 Oct 14;48(38):14505-14515. doi: 10.1039/c9dt03221e. Epub 2019 Sep 18. Dalton Trans. 2019. PMID: 31531475

7

'Carbon-Monoxide-Releasing Molecule-2 (CORM-2)' Is a Misnomer: Ruthenium Toxicity, Not CO Release, Accounts for Its Antimicrobial Effects.

Southam HM, Williamson MP, Chapman JA, Lyon RL, Trevitt CR, Henderson PJF, Poole RK. Southam HM, et al. Antioxidants (Basel). 2021 Jun 5;10(6):915. doi: 10.3390/antiox10060915. Antioxidants (Basel). 2021. PMID: 34198746 Free PMC article.

8

The Antimicrobial Activity of Mononuclear Ruthenium(II) Complexes Containing the dppz Ligand.

Liu X, Sun B, Kell REM, Southam HM, Butler JA, Li X, Poole RK, Keene FR, Collins JG. Liu X, et al. Among authors: southam hm. Chempluschem. 2018 Jul;83(7):643-650. doi: 10.1002/cplu.201800042. Epub 2018 Apr 20. Chempluschem. 2018. PMID: 31950622

9

Antibacterial activity of Mn(I) and Re(I) tricarbonyl complexes conjugated to a bile acid carrier molecule.

Betts JW, Roth P, Pattrick CA, Southam HM, La Ragione RM, Poole RK, Schatzschneider U. Betts JW, et al. Among authors: southam hm. Metallomics. 2020 Oct 21;12(10):1563-1575. doi: 10.1039/d0mt00142b. Metallomics. 2020. PMID: 32856674 Free article.

10

Synthesis, isomerisation and biological properties of mononuclear ruthenium complexes containing the bis[4(4'-methyl-2,2'-bipyridyl)]-1,7-heptane ligand.

Sun B , Southam HM , Butler JA , Poole RK , Burgun A , Tarzia A , Keene FR , Collins JG . Sun B , et al. Among authors: southam hm. Dalton Trans. 2018 Feb 13;47(7):2422-2434. doi: 10.1039/c7dt04595f. Dalton Trans. 2018. PMID: 29379923 Free article.

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