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Oxidative stress from DGAT1 oncoprotein inhibition in melanoma suppresses tumor growth when ROS defenses are also breached.
Wilcock DJ, Badrock AP, Wong CW, Owen R, Guerin M, Southam AD, Johnston H, Telfer BA, Fullwood P, Watson J, Ferguson H, Ferguson J, Lloyd GR, Jankevics A, Dunn WB, Wellbrock C, Lorigan P, Ceol C, Francavilla C, Smith MP, Hurlstone AFL. Wilcock DJ, et al. Among authors: guerin m. Cell Rep. 2022 Jun 21;39(12):110995. doi: 10.1016/j.celrep.2022.110995. Cell Rep. 2022. PMID: 35732120 Free PMC article.
Mechanisms of recalcitrant fucoidan breakdown in marine Planctomycetota.
Pérez-Cruz C, Moraleda-Montoya A, Liébana R, Terrones O, Arrizabalaga U, García-Alija M, Lorizate M, Martínez Gascueña A, García-Álvarez I, Nieto-Garai JA, Olazar-Intxausti J, Rodríguez-Colinas B, Mann E, Chiara JL, Contreras FX, Guerin ME, Trastoy B, Alonso-Sáez L. Pérez-Cruz C, et al. Among authors: guerin me. Nat Commun. 2024 Dec 30;15(1):10906. doi: 10.1038/s41467-024-55268-w. Nat Commun. 2024. PMID: 39738071 Free PMC article.
ABCG1 orchestrates adipose tissue macrophage plasticity and insulin resistance in obesity by rewiring saturated fatty acid pools.
Dahik VD, Kc P, Materne C, Reydellet C, Lhomme M, Cruciani-Guglielmacci C, Denom J, Bun E, Ponnaiah M, Deknuydt F, Frisdal E, Hardy LM, Durand H, Guillas I, Lesnik P, Gudelj I, Lauc G, Guérin M, Kontush A, Soprani A, Magnan C, Diedisheim M, Bluteau O, Venteclef N, Le Goff W. Dahik VD, et al. Among authors: guerin m. Sci Transl Med. 2024 Dec 11;16(777):eadi6682. doi: 10.1126/scitranslmed.adi6682. Epub 2024 Dec 11. Sci Transl Med. 2024. PMID: 39661702
Defective biological activities of high-density lipoprotein identify patients at highest risk of recurrent cardiovascular event.
Silvain J, Materne C, Zeitouni M, Procopi N, Guedeney P, Brugier D, Galier S, Lhomme M, Ponnaiah M, Guillas I, Kc P, Dahik VD, Frisdal E, Vicaut E, Lesnik P, Rahoual G, Le Goff W, Montalescot G, Kerneis M, Guerin M. Silvain J, et al. Among authors: guerin m. Eur J Prev Cardiol. 2024 Nov 7:zwae356. doi: 10.1093/eurjpc/zwae356. Online ahead of print. Eur J Prev Cardiol. 2024. PMID: 39506545
780 results