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Oxidative stress from DGAT1 oncoprotein inhibition in melanoma suppresses tumor growth when ROS defenses are also breached.
Wilcock DJ, Badrock AP, Wong CW, Owen R, Guerin M, Southam AD, Johnston H, Telfer BA, Fullwood P, Watson J, Ferguson H, Ferguson J, Lloyd GR, Jankevics A, Dunn WB, Wellbrock C, Lorigan P, Ceol C, Francavilla C, Smith MP, Hurlstone AFL. Wilcock DJ, et al. Among authors: johnston h. Cell Rep. 2022 Jun 21;39(12):110995. doi: 10.1016/j.celrep.2022.110995. Cell Rep. 2022. PMID: 35732120 Free PMC article.
Enhanced Fatty Acid Scavenging and Glycerophospholipid Metabolism Accompany Melanocyte Neoplasia Progression in Zebrafish.
Henderson F, Johnston HR, Badrock AP, Jones EA, Forster D, Nagaraju RT, Evangelou C, Kamarashev J, Green M, Fairclough M, Ramirez IB, He S, Snaar-Jagalska BE, Hollywood K, Dunn WB, Spaink HP, Smith MP, Lorigan P, Claude E, Williams KJ, McMahon AW, Hurlstone A. Henderson F, et al. Cancer Res. 2019 May 1;79(9):2136-2151. doi: 10.1158/0008-5472.CAN-18-2409. Epub 2019 Mar 12. Cancer Res. 2019. PMID: 30862716
Novel Macrocyclic NLRP3 Inhibitors.
Mesch S, Shannon J, Miller D, MacLeod A, Bouché L, Johnston HJ, Matthews K, Paehler A, Best S, Guba W, Alanine T, Halai R, Charge L, Garside S, Thom S, Incerti-Pradillos C, McPherson C, Carrillo J, St-Gallay S, Rigo P, Schlicht S, Hendrick AG, Lerner C, Piali L, Blaising J, Mracsko EZ, Jaeschke G, Cooper MA. Mesch S, et al. Among authors: johnston hj. J Med Chem. 2024 Dec 12;67(23):20911-20932. doi: 10.1021/acs.jmedchem.4c01376. Epub 2024 Nov 25. J Med Chem. 2024. PMID: 39585325
Spatial and temporal transmission dynamics of respiratory syncytial virus in New Zealand before and after the COVID-19 pandemic.
Jelley L, Douglas J, O'Neill M, Berquist K, Claasen A, Wang J, Utekar S, Johnston H, Bocacao J, Allais M, de Ligt J, Tan CE, Seeds R, Wood T, Aminisani N, Jennings T, Welch D, Turner N, McIntyre P, Dowell T, Trenholme A, Byrnes C; SHIVERS investigation team; Thomas P, Webby R, French N, Huang QS, Winter D, Geoghegan JL. Jelley L, et al. Among authors: johnston h. Nat Commun. 2024 Nov 11;15(1):9758. doi: 10.1038/s41467-024-53998-5. Nat Commun. 2024. PMID: 39528493 Free PMC article.
606 results