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Oxidative stress from DGAT1 oncoprotein inhibition in melanoma suppresses tumor growth when ROS defenses are also breached.
Wilcock DJ, Badrock AP, Wong CW, Owen R, Guerin M, Southam AD, Johnston H, Telfer BA, Fullwood P, Watson J, Ferguson H, Ferguson J, Lloyd GR, Jankevics A, Dunn WB, Wellbrock C, Lorigan P, Ceol C, Francavilla C, Smith MP, Hurlstone AFL. Wilcock DJ, et al. Cell Rep. 2022 Jun 21;39(12):110995. doi: 10.1016/j.celrep.2022.110995. Cell Rep. 2022. PMID: 35732120 Free PMC article.
Cooperative behaviour and phenotype plasticity evolve during melanoma progression.
Rowling EJ, Miskolczi Z, Nagaraju R, Wilcock DJ, Wang P, Telfer B, Li Y, Lasheras-Otero I, Redondo-Muñoz M, Sharrocks AD, Arozarena I, Wellbrock C. Rowling EJ, et al. Among authors: wilcock dj. Pigment Cell Melanoma Res. 2020 Sep;33(5):695-708. doi: 10.1111/pcmr.12873. Epub 2020 Mar 20. Pigment Cell Melanoma Res. 2020. PMID: 32145051 Free PMC article.
PARP14 inhibition restores PD-1 immune checkpoint inhibitor response following IFNγ-driven acquired resistance in preclinical cancer models.
Wong CW, Evangelou C, Sefton KN, Leshem R, Zhang W, Gopalan V, Chattrakarn S, Fernandez Carro ML, Uzuner E, Mole H, Wilcock DJ, Smith MP, Sergiou K, Telfer BA, Isaac DT, Liu C, Perl NR, Marie K, Lorigan P, Williams KJ, Rao PE, Nagaraju RT, Niepel M, Hurlstone AFL. Wong CW, et al. Among authors: wilcock dj. Nat Commun. 2023 Sep 26;14(1):5983. doi: 10.1038/s41467-023-41737-1. Nat Commun. 2023. PMID: 37752135 Free PMC article.
16 results