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A small molecule redistributes iron in ferroportin-deficient mice and patient-derived primary macrophages.
Ekaputri S, Choi EK, Sabelli M, Aring L, Green KJ, Chang J, Bao K, Choi HS, Iwase S, Kim J, Corradini E, Pietrangelo A, Burke MD, Seo YA. Ekaputri S, et al. Among authors: seo ya. Proc Natl Acad Sci U S A. 2022 Jun 28;119(26):e2121400119. doi: 10.1073/pnas.2121400119. Epub 2022 Jun 22. Proc Natl Acad Sci U S A. 2022. PMID: 35737834 Free PMC article.
Restored iron transport by a small molecule promotes absorption and hemoglobinization in animals.
Grillo AS, SantaMaria AM, Kafina MD, Cioffi AG, Huston NC, Han M, Seo YA, Yien YY, Nardone C, Menon AV, Fan J, Svoboda DC, Anderson JB, Hong JD, Nicolau BG, Subedi K, Gewirth AA, Wessling-Resnick M, Kim J, Paw BH, Burke MD. Grillo AS, et al. Among authors: seo ya. Science. 2017 May 12;356(6338):608-616. doi: 10.1126/science.aah3862. Science. 2017. PMID: 28495746 Free PMC article.
Impact of dietary manganese on experimental colitis in mice.
Choi EK, Aring L, Das NK, Solanki S, Inohara N, Iwase S, Samuelson LC, Shah YM, Seo YA. Choi EK, et al. Among authors: seo ya. FASEB J. 2020 Feb;34(2):2929-2943. doi: 10.1096/fj.201902396R. Epub 2019 Dec 29. FASEB J. 2020. PMID: 31908045 Free PMC article.
Minimizing higher-order aggregation maximizes iron mobilization by small molecules.
Blake AD, Chao J, SantaMaria AM, Ekaputri S, Green KJ, Brown ST, Rakowski CK, Choi EK, Aring L, Chen PJ, Snead NM, Matje DM, Geng T, Octaviani A, Bailey K, Hollenbach SJ, Fan TM, Seo YA, Burke MD. Blake AD, et al. Among authors: seo ya. Nat Chem Biol. 2024 Oct;20(10):1282-1293. doi: 10.1038/s41589-024-01596-3. Epub 2024 Apr 25. Nat Chem Biol. 2024. PMID: 38664586
55 results