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A genome-wide CRISPR-Cas9 screen identifies CENPJ as a host regulator of altered microtubule organization during Plasmodium liver infection.
Vijayan K, Arang N, Wei L, Morrison R, Geiger R, Parks KR, Lewis AJ, Mast FD, Douglass AN, Kain HS, Aitchison JD, Johnson JS, Aderem A, Kaushansky A. Vijayan K, et al. Among authors: douglass an. Cell Chem Biol. 2022 Sep 15;29(9):1419-1433.e5. doi: 10.1016/j.chembiol.2022.06.001. Epub 2022 Jun 22. Cell Chem Biol. 2022. PMID: 35738280 Free PMC article.
Liver stage malaria infection is controlled by host regulators of lipid peroxidation.
Kain HS, Glennon EKK, Vijayan K, Arang N, Douglass AN, Fortin CL, Zuck M, Lewis AJ, Whiteside SL, Dudgeon DR, Johnson JS, Aderem A, Stevens KR, Kaushansky A. Kain HS, et al. Among authors: douglass an. Cell Death Differ. 2020 Jan;27(1):44-54. doi: 10.1038/s41418-019-0338-1. Epub 2019 May 7. Cell Death Differ. 2020. PMID: 31065106 Free PMC article.
Suppression of host p53 is critical for Plasmodium liver-stage infection.
Kaushansky A, Ye AS, Austin LS, Mikolajczak SA, Vaughan AM, Camargo N, Metzger PG, Douglass AN, MacBeath G, Kappe SH. Kaushansky A, et al. Among authors: douglass an. Cell Rep. 2013 Mar 28;3(3):630-7. doi: 10.1016/j.celrep.2013.02.010. Epub 2013 Mar 7. Cell Rep. 2013. PMID: 23478020 Free PMC article.
Host-based Prophylaxis Successfully Targets Liver Stage Malaria Parasites.
Douglass AN, Kain HS, Abdullahi M, Arang N, Austin LS, Mikolajczak SA, Billman ZP, Hume JCC, Murphy SC, Kappe SHI, Kaushansky A. Douglass AN, et al. Mol Ther. 2015 May;23(5):857-865. doi: 10.1038/mt.2015.18. Epub 2015 Feb 4. Mol Ther. 2015. PMID: 25648263 Free PMC article.
13 results