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A genome-wide CRISPR-Cas9 screen identifies CENPJ as a host regulator of altered microtubule organization during Plasmodium liver infection.
Vijayan K, Arang N, Wei L, Morrison R, Geiger R, Parks KR, Lewis AJ, Mast FD, Douglass AN, Kain HS, Aitchison JD, Johnson JS, Aderem A, Kaushansky A. Vijayan K, et al. Among authors: kain hs. Cell Chem Biol. 2022 Sep 15;29(9):1419-1433.e5. doi: 10.1016/j.chembiol.2022.06.001. Epub 2022 Jun 22. Cell Chem Biol. 2022. PMID: 35738280 Free PMC article.
Liver stage malaria infection is controlled by host regulators of lipid peroxidation.
Kain HS, Glennon EKK, Vijayan K, Arang N, Douglass AN, Fortin CL, Zuck M, Lewis AJ, Whiteside SL, Dudgeon DR, Johnson JS, Aderem A, Stevens KR, Kaushansky A. Kain HS, et al. Cell Death Differ. 2020 Jan;27(1):44-54. doi: 10.1038/s41418-019-0338-1. Epub 2019 May 7. Cell Death Differ. 2020. PMID: 31065106 Free PMC article.
Host-based Prophylaxis Successfully Targets Liver Stage Malaria Parasites.
Douglass AN, Kain HS, Abdullahi M, Arang N, Austin LS, Mikolajczak SA, Billman ZP, Hume JCC, Murphy SC, Kappe SHI, Kaushansky A. Douglass AN, et al. Among authors: kain hs. Mol Ther. 2015 May;23(5):857-865. doi: 10.1038/mt.2015.18. Epub 2015 Feb 4. Mol Ther. 2015. PMID: 25648263 Free PMC article.
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