Lee KR - Search Results

1

A population PK-PD model of YH4808, a novel P-CAB, and intragastric pH that incorporated negative feedback by increased intragastric pH onto the systemic exposure to YH4808.

Chung TK, Lee HA, Lee KR, Jang SB, Yu KS, Lee H. Chung TK, et al. Among authors: lee kr, lee ha, lee h. CPT Pharmacometrics Syst Pharmacol. 2022 Sep;11(9):1223-1233. doi: 10.1002/psp4.12839. Epub 2022 Jul 9. CPT Pharmacometrics Syst Pharmacol. 2022. PMID: 35748058 Free PMC article.

2

A physiologically-based pharmacokinetic model adequately predicted the human pharmacokinetic profiles of YH4808, a novel K⁺-competitive acid blocker.

Lee HA, Lee KR, Jang SB, Chung SY, Yu KS, Lee H. Lee HA, et al. Among authors: lee kr, lee h. Eur J Pharm Sci. 2019 Mar 15;130:1-10. doi: 10.1016/j.ejps.2019.01.009. Epub 2019 Jan 11. Eur J Pharm Sci. 2019. PMID: 30641142 Clinical Trial.

3

A Machine Learning-Based Identification of Genes Affecting the Pharmacokinetics of Tacrolimus Using the DMET^TM Plus Platform.

Gim JA, Kwon Y, Lee HA, Lee KR, Kim S, Choi Y, Kim YK, Lee H. Gim JA, et al. Among authors: lee kr, lee ha, lee h. Int J Mol Sci. 2020 Apr 4;21(7):2517. doi: 10.3390/ijms21072517. Int J Mol Sci. 2020. PMID: 32260456 Free PMC article.

4

Integration of a Physiologically Based Pharmacokinetic and Pharmacodynamic Model for Tegoprazan and Its Metabolite: Application for Predicting Food Effect and Intragastric pH Alterations.

Jeong HC, Kim MG, Wei Z, Lee KR, Lee J, Song IS, Shin KH. Jeong HC, et al. Among authors: lee kr, lee j. Pharmaceutics. 2022 Jun 18;14(6):1298. doi: 10.3390/pharmaceutics14061298. Pharmaceutics. 2022. PMID: 35745870 Free PMC article.

5

Pharmacokinetics and pharmacodynamics of KR-66223, a novel DPP-4 inhibitor.

Song JS, Lee KR, Kwon HJ, Rhee SD, Kim MS, Choi SH, Lee SH, Song IS, Ahn JH, Ahn SH, Bae MA. Song JS, et al. Among authors: lee sh, lee kr. Drug Metab Pharmacokinet. 2012;27(2):216-22. doi: 10.2133/dmpk.dmpk-11-rg-095. Epub 2012 Jan 13. Drug Metab Pharmacokinet. 2012. PMID: 22240842 Free article.

6

Pharmacokinetics of fluconazole after oral administration to healthy beagle dogs.

Choi Y, Koo Y, Yun T, Chae Y, Lee D, Jeong JW, Lee KR, Kim H, Yang MP, Kang BT. Choi Y, et al. Among authors: lee d, lee kr. Vet Dermatol. 2022 Dec;33(6):509-515. doi: 10.1111/vde.13112. Epub 2022 Aug 24. Vet Dermatol. 2022. PMID: 36000582

7

A Preliminary Study of Pharmacokinetics and Pharmacodynamics of Oral Fingolimod in Dogs.

Yun T, Jeong JW, Koo Y, Chae Y, Lee D, Kim H, Kim S, Yang MP, Lee KR, Kang BT. Yun T, et al. Among authors: lee d, lee kr. In Vivo. 2023 Sep-Oct;37(5):2128-2133. doi: 10.21873/invivo.13309. In Vivo. 2023. PMID: 37652477 Free PMC article.

8

Model-based pharmacokinetic and pharmacodynamic analysis for acute effects of a small molecule inhibitor of diacylglycerol acyltransferase-1 in the TallyHo/JngJ polygenic mouse.

Chae YJ, Song JS, Ahn JH, Bae MA, Lee KR. Chae YJ, et al. Among authors: lee kr. Xenobiotica. 2019 Jul;49(7):823-832. doi: 10.1080/00498254.2018.1496303. Epub 2018 Sep 5. Xenobiotica. 2019. PMID: 29972081

9

Development of Physiologically Based Pharmacokinetic Model for Orally Administered Fexuprazan in Humans.

Jeong YS, Kim MS, Lee N, Lee A, Chae YJ, Chung SJ, Lee KR. Jeong YS, et al. Among authors: lee kr, lee n, lee a. Pharmaceutics. 2021 May 29;13(6):813. doi: 10.3390/pharmaceutics13060813. Pharmaceutics. 2021. PMID: 34072547 Free PMC article.

10

Model-Based Prediction of Acid Suppression and Proposal of a New Dosing Regimen of Fexuprazan in Humans.

Kim MS, Lee N, Lee A, Chae YJ, Chung SJ, Lee KR. Kim MS, et al. Among authors: lee kr, lee n, lee a. Pharmaceuticals (Basel). 2022 Jun 3;15(6):709. doi: 10.3390/ph15060709. Pharmaceuticals (Basel). 2022. PMID: 35745628 Free PMC article.

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