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BET Bromodomain Inhibitors with One-Step Synthesis Discovered from Virtual Screen.
Ayoub AM, Hawk LML, Herzig RJ, Jiang J, Wisniewski AJ, Gee CT, Zhao P, Zhu JY, Berndt N, Offei-Addo NK, Scott TG, Qi J, Bradner JE, Ward TR, Schönbrunn E, Georg GI, Pomerantz WCK. Ayoub AM, et al. Among authors: pomerantz wck. J Med Chem. 2017 Jun 22;60(12):4805-4817. doi: 10.1021/acs.jmedchem.6b01336. Epub 2017 Jun 7. J Med Chem. 2017. PMID: 28535045 Free PMC article.
Correction to BET Bromodomain Inhibitors with One-Step Synthesis Discovered from Virtual Screen.
Ayoub AM, Hawk LML, Herzig RJ, Jiang J, Wisniewski AJ, Gee CT, Zhao P, Zhu JY, Berndt N, Offei-Addo NK, Scott TG, Qi J, Bradner JE, Ward TR, Schönbrunn E, Georg GI, Pomerantz WCK. Ayoub AM, et al. Among authors: pomerantz wck. J Med Chem. 2017 Jul 27;60(14):6458. doi: 10.1021/acs.jmedchem.7b00943. Epub 2017 Jul 11. J Med Chem. 2017. PMID: 28696689 No abstract available.
Molecular Basis for the N-Terminal Bromodomain-and-Extra-Terminal-Family Selectivity of a Dual Kinase-Bromodomain Inhibitor.
Divakaran A, Talluri SK, Ayoub AM, Mishra NK, Cui H, Widen JC, Berndt N, Zhu JY, Carlson AS, Topczewski JJ, Schonbrunn EK, Harki DA, Pomerantz WCK. Divakaran A, et al. Among authors: pomerantz wck. J Med Chem. 2018 Oct 25;61(20):9316-9334. doi: 10.1021/acs.jmedchem.8b01248. Epub 2018 Oct 16. J Med Chem. 2018. PMID: 30253095 Free PMC article.
Selectivity, ligand deconstruction, and cellular activity analysis of a BPTF bromodomain inhibitor.
Kirberger SE, Ycas PD, Johnson JA, Chen C, Ciccone MF, Woo RWL, Urick AK, Zahid H, Shi K, Aihara H, McAllister SD, Kashani-Sabet M, Shi J, Dickson A, Dos Santos CO, Pomerantz WCK. Kirberger SE, et al. Among authors: pomerantz wck. Org Biomol Chem. 2019 Feb 13;17(7):2020-2027. doi: 10.1039/c8ob02599a. Org Biomol Chem. 2019. PMID: 30706071 Free PMC article.
94 results