Cong L - Search Results

1

Machine-learning-optimized Cas12a barcoding enables the recovery of single-cell lineages and transcriptional profiles.

Hughes NW, Qu Y, Zhang J, Tang W, Pierce J, Wang C, Agrawal A, Morri M, Neff N, Winslow MM, Wang M, Cong L. Hughes NW, et al. Among authors: cong l. Mol Cell. 2022 Aug 18;82(16):3103-3118.e8. doi: 10.1016/j.molcel.2022.06.001. Epub 2022 Jun 24. Mol Cell. 2022. PMID: 35752172 Free PMC article.

2

A Functional Taxonomy of Tumor Suppression in Oncogenic KRAS-Driven Lung Cancer.

Cai H, Chew SK, Li C, Tsai MK, Andrejka L, Murray CW, Hughes NW, Shuldiner EG, Ashkin EL, Tang R, Hung KL, Chen LC, Lee SYC, Yousefi M, Lin WY, Kunder CA, Cong L, McFarland CD, Petrov DA, Swanton C, Winslow MM. Cai H, et al. Among authors: cong l. Cancer Discov. 2021 Jul;11(7):1754-1773. doi: 10.1158/2159-8290.CD-20-1325. Epub 2021 Feb 19. Cancer Discov. 2021. PMID: 33608386 Free PMC article.

3

Microbial single-strand annealing proteins enable CRISPR gene-editing tools with improved knock-in efficiencies and reduced off-target effects.

Wang C, Cheng JKW, Zhang Q, Hughes NW, Xia Q, Winslow MM, Cong L. Wang C, et al. Among authors: cong l. Nucleic Acids Res. 2021 Apr 6;49(6):e36. doi: 10.1093/nar/gkaa1264. Nucleic Acids Res. 2021. PMID: 33619540 Free PMC article.

4

A CRISPR Landing for Genome Rewriting at Locus-Scale.

Hughes NW, Cong L. Hughes NW, et al. Among authors: cong l. CRISPR J. 2021 Apr;4(2):163-166. doi: 10.1089/crispr.2021.29124.lec. CRISPR J. 2021. PMID: 33876954 Free PMC article. No abstract available.

5

dCas9-based gene editing for cleavage-free genomic knock-in of long sequences.

Wang C, Qu Y, Cheng JKW, Hughes NW, Zhang Q, Wang M, Cong L. Wang C, et al. Among authors: cong l. Nat Cell Biol. 2022 Feb;24(2):268-278. doi: 10.1038/s41556-021-00836-1. Epub 2022 Feb 10. Nat Cell Biol. 2022. PMID: 35145221 Free PMC article.

6

CRISPR-Cas12a System With Synergistic Phage Recombination Proteins for Multiplex Precision Editing in Human Cells.

Wang C, Xia Q, Zhang Q, Qu Y, Su S, Cheng JKW, Hughes NW, Cong L. Wang C, et al. Among authors: cong l. Front Cell Dev Biol. 2022 Jun 14;9:719705. doi: 10.3389/fcell.2021.719705. eCollection 2021. Front Cell Dev Biol. 2022. PMID: 35774104 Free PMC article.

7

Efficient and multiplexed somatic genome editing with Cas12a mice.

Hebert JD, Xu H, Tang YJ, Ruiz PA, Detrick CR, Wang J, Hughes NW, Donosa O, Andrejka L, Karmakar S, Aboiralor I, Tang R, Sage J, Cong L, Petrov DA, Winslow MM. Hebert JD, et al. Among authors: cong l. bioRxiv [Preprint]. 2024 May 25:2024.03.07.583774. doi: 10.1101/2024.03.07.583774. bioRxiv. 2024. PMID: 38496463 Free PMC article. Preprint.

8

Computationally guided high-throughput engineering of an anti-CRISPR protein for precise genome editing in human cells.

Marsiglia J, Vaalavirta K, Knight E, Nakamura M, Cong L, Hughes NW. Marsiglia J, et al. Among authors: cong l. Cell Rep Methods. 2024 Oct 21;4(10):100882. doi: 10.1016/j.crmeth.2024.100882. Cell Rep Methods. 2024. PMID: 39437714 Free PMC article.

9

CRISPR-GPT: An LLM Agent for Automated Design of Gene-Editing Experiments.

Qu Y, Huang K, Cousins H, Johnson WA, Yin D, Shah M, Zhou D, Altman R, Wang M, Cong L. Qu Y, et al. Among authors: cong l. bioRxiv [Preprint]. 2024 Oct 15:2024.04.25.591003. doi: 10.1101/2024.04.25.591003. bioRxiv. 2024. PMID: 39463961 Free PMC article. Preprint.

10

Genome engineering using CRISPR-Cas9 system.

Cong L, Zhang F. Cong L, et al. Methods Mol Biol. 2015;1239:197-217. doi: 10.1007/978-1-4939-1862-1_10. Methods Mol Biol. 2015. PMID: 25408407

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