Lei H - Search Results

1

Semi-deconvolution of bulk and single-cell RNA-seq data with application to metastatic progression in breast cancer.

Lei H, Guo XA, Tao Y, Ding K, Fu X, Oesterreich S, Lee AV, Schwartz R. Lei H, et al. Bioinformatics. 2022 Jun 24;38(Suppl 1):i386-i394. doi: 10.1093/bioinformatics/btac262. Bioinformatics. 2022. PMID: 35758822 Free PMC article.

2

Tumor Copy Number Deconvolution Integrating Bulk and Single-Cell Sequencing Data.

Lei H, Lyu B, Gertz EM, Schäffer AA, Shi X, Wu K, Li G, Xu L, Hou Y, Dean M, Schwartz R. Lei H, et al. J Comput Biol. 2020 Apr;27(4):565-598. doi: 10.1089/cmb.2019.0302. Epub 2020 Mar 16. J Comput Biol. 2020. PMID: 32181683 Free PMC article.

3

Robust and accurate deconvolution of tumor populations uncovers evolutionary mechanisms of breast cancer metastasis.

Tao Y, Lei H, Fu X, Lee AV, Ma J, Schwartz R. Tao Y, et al. Among authors: lei h. Bioinformatics. 2020 Jul 1;36(Suppl_1):i407-i416. doi: 10.1093/bioinformatics/btaa396. Bioinformatics. 2020. PMID: 32657393 Free PMC article.

4

Neural Network Deconvolution Method for Resolving Pathway-Level Progression of Tumor Clonal Expression Programs With Application to Breast Cancer Brain Metastases.

Tao Y, Lei H, Lee AV, Ma J, Schwartz R. Tao Y, et al. Among authors: lei h. Front Physiol. 2020 Sep 4;11:1055. doi: 10.3389/fphys.2020.01055. eCollection 2020. Front Physiol. 2020. PMID: 33013452 Free PMC article.

5

Tumor heterogeneity assessed by sequencing and fluorescence in situ hybridization (FISH) data.

Lei H, Gertz EM, Schäffer AA, Fu X, Tao Y, Heselmeyer-Haddad K, Torres I, Li G, Xu L, Hou Y, Wu K, Shi X, Dean M, Ried T, Schwartz R. Lei H, et al. Bioinformatics. 2021 Dec 11;37(24):4704-4711. doi: 10.1093/bioinformatics/btab504. Bioinformatics. 2021. PMID: 34289030 Free PMC article.

6

Joint Clustering of Single-Cell Sequencing and Fluorescence In Situ Hybridization Data for Reconstructing Clonal Heterogeneity in Cancers.

Fu X, Lei H, Tao Y, Heselmeyer-Haddad K, Torres I, Dean M, Ried T, Schwartz R. Fu X, et al. Among authors: lei h. J Comput Biol. 2021 Nov;28(11):1035-1051. doi: 10.1089/cmb.2021.0255. Epub 2021 Oct 5. J Comput Biol. 2021. PMID: 34612714 Free PMC article.

7

Reconstructing tumor clonal lineage trees incorporating single-nucleotide variants, copy number alterations and structural variations.

Fu X, Lei H, Tao Y, Schwartz R. Fu X, et al. Among authors: lei h. Bioinformatics. 2022 Jun 24;38(Suppl 1):i125-i133. doi: 10.1093/bioinformatics/btac253. Bioinformatics. 2022. PMID: 35758777 Free PMC article.

8

A Clonal Evolution Simulator for Planning Somatic Evolution Studies.

Srivatsa A, Lei H, Schwartz R. Srivatsa A, et al. Among authors: lei h. J Comput Biol. 2023 Aug;30(8):831-847. doi: 10.1089/cmb.2023.0086. Epub 2023 May 15. J Comput Biol. 2023. PMID: 37184853 Free PMC article.

9

Kinetic and Affinity Profiling Rare Earth Metals Using a DNA Aptamer.

Wang J, Kaiyum YA, Li X, Lei H, Johnson PE, Liu J. Wang J, et al. Among authors: lei h. J Am Chem Soc. 2025 Jan 1. doi: 10.1021/jacs.4c13768. Online ahead of print. J Am Chem Soc. 2025. PMID: 39743479

10

Deciphering the N¹-substituent effects on biodegradation of sulfonamides: Novel insights revealed from molecular biology and computational chemistry approaches.

Hu J, Li R, Zhang J, Cao L, Lei H, Zhao R, Lin L, Li XY, Zhang W, Li B. Hu J, et al. Among authors: lei h. Water Res. 2024 Dec 25;274:123037. doi: 10.1016/j.watres.2024.123037. Online ahead of print. Water Res. 2024. PMID: 39740328

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