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Generation of nanobodies from transgenic 'LamaMice' lacking an endogenous immunoglobulin repertoire.
Eden T, Schaffrath AZ, Wesolowski J, Stähler T, Tode N, Richter N, Schäfer W, Hambach J, Hermans-Borgmeyer I, Woens J, Le Gall CM, Wendler S, Linke-Winnebeck C, Stobbe M, Budnicki I, Wanney A, Heitz Y, Schimmelpfennig L, Schweitzer L, Zimmer D, Stahl E, Seyfried F, Gebhardt AJ, Dieckow L, Riecken K, Fehse B, Bannas P, Magnus T, Verdoes M, Figdor CG, Hartlepp KF, Schleer H, Füner J, Tomas NM, Haag F, Rissiek B, Mann AM, Menzel S, Koch-Nolte F. Eden T, et al. Among authors: heitz y. Nat Commun. 2024 Jun 3;15(1):4728. doi: 10.1038/s41467-024-48735-x. Nat Commun. 2024. PMID: 38830864 Free PMC article.
BAFFR activates PI3K/AKT signaling in human naive but not in switched memory B cells through direct interactions with B cell antigen receptors.
Sevdali E, Block V, Lataretu M, Li H, Smulski CR, Briem JS, Heitz Y, Fischer B, Ramirez NJ, Grimbacher B, Jäck HM, Voll RE, Hölzer M, Schneider P, Eibel H. Sevdali E, et al. Among authors: heitz y. Cell Rep. 2022 Jun 28;39(13):111019. doi: 10.1016/j.celrep.2022.111019. Cell Rep. 2022. PMID: 35767961 Free article.