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Page 1
Changes over time in characteristics, resource use and outcomes among ICU patients with COVID-19-A nationwide, observational study in Denmark.
Haase N, Plovsing R, Christensen S, Poulsen LM, Brøchner AC, Rasmussen BS, Helleberg M, Jensen JUS, Andersen LPK, Siegel H, Ibsen M, Jørgensen VL, Winding R, Iversen S, Pedersen HP, Madsen J, Sølling C, Garcia RS, Michelsen J, Mohr T, Michagin G, Espelund US, Bundgaard H, Kirkegaard L, Smitt M, Buck DL, Ribergaard NE, Pedersen HS, Christensen BV, Nielsen LP, Clapp E, Jonassen TB, Weihe S, la Cour K, Nielsen FM, Madsen EK, Haberlandt TN, Meier N, Perner A. Haase N, et al. Among authors: weihe s. Acta Anaesthesiol Scand. 2022 Sep;66(8):987-995. doi: 10.1111/aas.14113. Epub 2022 Aug 2. Acta Anaesthesiol Scand. 2022. PMID: 35781689 Free PMC article.
Effect of 12 mg vs 6 mg of Dexamethasone on the Number of Days Alive Without Life Support in Adults With COVID-19 and Severe Hypoxemia: The COVID STEROID 2 Randomized Trial.
COVID STEROID 2 Trial Group; Munch MW, Myatra SN, Vijayaraghavan BKT, Saseedharan S, Benfield T, Wahlin RR, Rasmussen BS, Andreasen AS, Poulsen LM, Cioccari L, Khan MS, Kapadia F, Divatia JV, Brøchner AC, Bestle MH, Helleberg M, Michelsen J, Padmanaban A, Bose N, Møller A, Borawake K, Kristiansen KT, Shukla U, Chew MS, Dixit S, Ulrik CS, Amin PR, Chawla R, Wamberg CA, Shah MS, Darfelt IS, Jørgensen VL, Smitt M, Granholm A, Kjær MN, Møller MH, Meyhoff TS, Vesterlund GK, Hammond NE, Micallef S, Bassi A, John O, Jha A, Cronhjort M, Jakob SM, Gluud C, Lange T, Kadam V, Marcussen KV, Hollenberg J, Hedman A, Nielsen H, Schjørring OL, Jensen MQ, Leistner JW, Jonassen TB, Kristensen CM, Clapp EC, Hjortsø CJS, Jensen TS, Halstad LS, Bak ERB, Zaabalawi R, Metcalf-Clausen M, Abdi S, Hatley EV, Aksnes TS, Gleipner-Andersen E, Alarcón AF, Yamin G, Heymowski A, Berggren A, La Cour K, Weihe S, Pind AH, Engstrøm J, Jha V, Venkatesh B, Perner A. COVID STEROID 2 Trial Group, et al. Among authors: weihe s. JAMA. 2021 Nov 9;326(18):1807-1817. doi: 10.1001/jama.2021.18295. JAMA. 2021. PMID: 34673895 Free PMC article. Clinical Trial.
Restriction of Intravenous Fluid in ICU Patients with Septic Shock.
Meyhoff TS, Hjortrup PB, Wetterslev J, Sivapalan P, Laake JH, Cronhjort M, Jakob SM, Cecconi M, Nalos M, Ostermann M, Malbrain M, Pettilä V, Møller MH, Kjær MN, Lange T, Overgaard-Steensen C, Brand BA, Winther-Olesen M, White JO, Quist L, Westergaard B, Jonsson AB, Hjortsø CJS, Meier N, Jensen TS, Engstrøm J, Nebrich L, Andersen-Ranberg NC, Jensen JV, Joseph NA, Poulsen LM, Herløv LS, Sølling CG, Pedersen SK, Knudsen KK, Straarup TS, Vang ML, Bundgaard H, Rasmussen BS, Aagaard SR, Hildebrandt T, Russell L, Bestle MH, Schønemann-Lund M, Brøchner AC, Elvander CF, Hoffmann SKL, Rasmussen ML, Martin YK, Friberg FF, Seter H, Aslam TN, Ådnøy S, Seidel P, Strand K, Johnstad B, Joelsson-Alm E, Christensen J, Ahlstedt C, Pfortmueller CA, Siegemund M, Greco M, Raděj J, Kříž M, Gould DW, Rowan KM, Mouncey PR, Perner A; CLASSIC Trial Group. Meyhoff TS, et al. N Engl J Med. 2022 Jun 30;386(26):2459-2470. doi: 10.1056/NEJMoa2202707. Epub 2022 Jun 17. N Engl J Med. 2022. PMID: 35709019 Clinical Trial.
Long-term cognitive and functional status in Danish ICU patients with COVID-19.
Weihe S, Mortensen CB, Haase N, Andersen LPK, Mohr T, Siegel H, Ibsen M, Jørgensen VRL, Buck DL, Pedersen HBS, Pedersen HP, Iversen S, Ribergaard N, Rasmussen BS, Winding R, Espelund US, Bundgaard H, Sølling CG, Christensen S, Garcia RS, Brøchner AC, Michelsen J, Michagin G, Kirkegaard L, Perner A, Mathiesen O, Poulsen LM. Weihe S, et al. Acta Anaesthesiol Scand. 2022 Sep;66(8):978-986. doi: 10.1111/aas.14108. Epub 2022 Jul 13. Acta Anaesthesiol Scand. 2022. PMID: 35748019 Free PMC article.
Thromboembolic and bleeding events in ICU patients with COVID-19: A nationwide, observational study.
Russell L, Weihe S, Madsen EK, Hvas CL, Leistner JW, Michelsen J, Brøchner AC, Bastiansen A, Nielsen FM, Meier N, Andreasen AS, Ribergaard NE, Rasmussen BS, Sølling CG, Buck DL, Bundgaard H, Pedersen HS, Darfelt IS, Poulsen LM, Ibsen M, Plovsing RR, Sigurdsson ST, Iversen S, Hildebrandt T, Mohr T, Espelund US, Jørgensen V, Haase N, Perner A. Russell L, et al. Among authors: weihe s. Acta Anaesthesiol Scand. 2023 Jan;67(1):76-85. doi: 10.1111/aas.14157. Epub 2022 Nov 6. Acta Anaesthesiol Scand. 2023. PMID: 36263897 Free PMC article.
Haloperidol for the Treatment of Delirium in ICU Patients.
Andersen-Ranberg NC, Poulsen LM, Perner A, Wetterslev J, Estrup S, Hästbacka J, Morgan M, Citerio G, Caballero J, Lange T, Kjær MN, Ebdrup BH, Engstrøm J, Olsen MH, Oxenbøll Collet M, Mortensen CB, Weber SO, Andreasen AS, Bestle MH, Uslu B, Scharling Pedersen H, Gramstrup Nielsen L, Toft Boesen HC, Jensen JV, Nebrich L, La Cour K, Laigaard J, Haurum C, Olesen MW, Overgaard-Steensen C, Westergaard B, Brand B, Kingo Vesterlund G, Thornberg Kyhnauv P, Mikkelsen VS, Hyttel-Sørensen S, de Haas I, Aagaard SR, Nielsen LO, Eriksen AS, Rasmussen BS, Brix H, Hildebrandt T, Schønemann-Lund M, Fjeldsøe-Nielsen H, Kuivalainen AM, Mathiesen O; AID-ICU Trial Group. Andersen-Ranberg NC, et al. N Engl J Med. 2022 Dec 29;387(26):2425-2435. doi: 10.1056/NEJMoa2211868. Epub 2022 Oct 26. N Engl J Med. 2022. PMID: 36286254 Clinical Trial.
Effects of 12 mg vs. 6 mg dexamethasone on thromboembolism and bleeding in patients with critical COVID-19 - a post hoc analysis of the randomized, blinded COVID STEROID 2 trial.
Jonmarker S, Alarcón F, Litorell J, Granholm A, Alm EJ, Chew M, Russell L, Weihe S, Madsen EK, Meier N, Leistner JW, Mårtensson J, Hollenberg J, Perner A, Kjær MN, Munch MW, Dahlberg M, Cronhjort M, Wahlin RR. Jonmarker S, et al. Among authors: weihe s. Ann Intensive Care. 2023 Mar 2;13(1):12. doi: 10.1186/s13613-023-01115-y. Ann Intensive Care. 2023. PMID: 36862239 Free PMC article.
Heterogeneity of treatment effect of higher dose dexamethasone by geographic region (Europe vs. India) in patients with COVID-19 and severe hypoxemia - a post hoc evaluation of the COVID STEROID 2 trial.
Tirupakuzhi Vijayaraghavan BK, Granholm A, Myatra SN, Jha V, Hammond N, Micallef S, Munch MW, Kjær MN, Møller MH, Lange T, Perner A, Venkatesh B; COVID-STEROID 2 collaborators. Tirupakuzhi Vijayaraghavan BK, et al. Lancet Reg Health Southeast Asia. 2023 Oct 4;20:100293. doi: 10.1016/j.lansea.2023.100293. eCollection 2024 Jan. Lancet Reg Health Southeast Asia. 2023. PMID: 38234702 Free PMC article.
Lower vs Higher Oxygenation Target and Days Alive Without Life Support in COVID-19: The HOT-COVID Randomized Clinical Trial.
Nielsen FM, Klitgaard TL, Siegemund M, Laake JH, Thormar KM, Cole JM, Aagaard SR, Bunzel AG, Vestergaard SR, Langhoff PK, Pedersen CH, Hejlesen JØ, Abdelhamid S, Dietz A, Gebhard CE, Zellweger N, Hollinger A, Poulsen LM, Weihe S, Andersen-Ranberg NC, Pedersen UG, Mathiesen O, Andreasen AS, Brix H, Thomsen JJ, Petersen CH, Bestle MH, Wichmann S, Lund MS, Mortensen KM, Brand BA, Haase N, Iversen SA, Marcussen KV, Brøchner AC, Borup M, Grøfte T, Hildebrandt T, Kjær MN, Engstrøm J, Lange T, Perner A, Schjørring OL, Rasmussen BS; HOT-COVID Trial Group. Nielsen FM, et al. Among authors: weihe s. JAMA. 2024 Apr 9;331(14):1185-1194. doi: 10.1001/jama.2024.2934. JAMA. 2024. PMID: 38501214 Free PMC article.
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