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Structural Optimization of siRNA Conjugates for Albumin Binding Achieves Effective MCL1-Targeted Cancer Therapy.
Hoogenboezem EN, Patel SS, Cavnar AB, Lo JH, Babb LM, Francini N, Patil P, Colazo JM, Michell DL, Sanchez VM, McCune JT, Ma J, DeJulius CR, Lee LH, Rosch JC, Allen RM, Stokes LD, Hill JL, Vickers KC, Cook RS, Duvall CL. Hoogenboezem EN, et al. Among authors: lo jh. bioRxiv [Preprint]. 2023 Feb 15:2023.02.14.528574. doi: 10.1101/2023.02.14.528574. bioRxiv. 2023. Update in: Nat Commun. 2024 Feb 21;15(1):1581. doi: 10.1038/s41467-024-45609-0 PMID: 36824780 Free PMC article. Updated. Preprint.
Core polymer optimization of ternary siRNA nanoparticles enhances in vivo safety, pharmacokinetics, and tumor gene silencing.
Patel SS, Hoogenboezem EN, Yu F, DeJulius CR, Fletcher RB, Sorets AG, Cherry FK, Lo JH, Bezold MG, Francini N, d'Arcy R, Brasuell JE, Cook RS, Duvall CL. Patel SS, et al. Among authors: lo jh. Biomaterials. 2023 Jun;297:122098. doi: 10.1016/j.biomaterials.2023.122098. Epub 2023 Mar 28. Biomaterials. 2023. PMID: 37031547 Free PMC article.
Structural optimization of siRNA conjugates for albumin binding achieves effective MCL1-directed cancer therapy.
Hoogenboezem EN, Patel SS, Lo JH, Cavnar AB, Babb LM, Francini N, Gbur EF, Patil P, Colazo JM, Michell DL, Sanchez VM, McCune JT, Ma J, DeJulius CR, Lee LH, Rosch JC, Allen RM, Stokes LD, Hill JL, Vickers KC, Cook RS, Duvall CL. Hoogenboezem EN, et al. Among authors: lo jh. Nat Commun. 2024 Feb 21;15(1):1581. doi: 10.1038/s41467-024-45609-0. Nat Commun. 2024. PMID: 38383524 Free PMC article.
Comprehensive characterization of MCL-1 in patients with colorectal cancer: Expression, molecular profiles, and outcomes.
Mittal P, Battaglin F, Baca Y, Xiu J, Farrell A, Soni S, Lo JH, Torres-Gonzalez L, Algaze S, Jayachandran P, Ashouri K, Wong A, Zhang W, Yu J, Zhang L, Weinberg BA, Lou E, Shields AF, Goldberg RM, Marshall JL, Goel S, Singh IK, Lenz HJ. Mittal P, et al. Among authors: lo jh. Int J Cancer. 2024 Dec 30. doi: 10.1002/ijc.35304. Online ahead of print. Int J Cancer. 2024. PMID: 39740007
Role of CD47 gene expression in colorectal cancer: a comprehensive molecular profiling study.
Arai H, Gandhi N, Battaglin F, Wang J, Algaze S, Jayachandran P, Soni S, Zhang W, Yang Y, Millstein J, Lo JH, Sohal D, Goldberg R, Hall MJ, Scott AJ, Hwang JJ, Lou E, Weinberg BA, Marshall J, Goel S, Xiu J, Korn WM, Lenz HJ. Arai H, et al. Among authors: lo jh. J Immunother Cancer. 2024 Nov 5;12(11):e010326. doi: 10.1136/jitc-2024-010326. J Immunother Cancer. 2024. PMID: 39500526 Free article.
Polymeric Micellar Nanoparticles Enable Image-guided Drug Delivery in Solid Tumors.
Uddin J, Oltman CG, Lo JH, Gupta MK, Werfel TA, Mohyuddin M, Nazmin F, Rahman S, Crews BC, Kingsley PJ, Marnett LJ, Duvall CL, Cook RS. Uddin J, et al. Among authors: lo jh. bioRxiv [Preprint]. 2024 Jun 10:2024.06.07.598019. doi: 10.1101/2024.06.07.598019. bioRxiv. 2024. PMID: 38915607 Free PMC article. Preprint.
67 results