Porcù E - Search Results

1

Identification of Homoharringtonine as a potent inhibitor of glioblastoma cell proliferation and migration.

Porcù E, Maule F, Manfreda L, Mariotto E, Bresolin S, Cani A, Bortolozzi R, Della Puppa A, Corallo D, Viola G, Rampazzo E, Persano L. Porcù E, et al. Transl Res. 2023 Jan;251:41-53. doi: 10.1016/j.trsl.2022.06.017. Epub 2022 Jul 3. Transl Res. 2023. PMID: 35788055

2

Discovery and optimization of a series of 2-aryl-4-amino-5-(3',4',5'-trimethoxybenzoyl)thiazoles as novel anticancer agents.

Romagnoli R, Baraldi PG, Salvador MK, Preti D, Aghazadeh Tabrizi M, Brancale A, Fu XH, Li J, Zhang SZ, Hamel E, Bortolozzi R, Porcù E, Basso G, Viola G. Romagnoli R, et al. Among authors: porcu e. J Med Chem. 2012 Jun 14;55(11):5433-45. doi: 10.1021/jm300388h. Epub 2012 May 21. J Med Chem. 2012. PMID: 22578111 Free PMC article.

3

TR-644 a novel potent tubulin binding agent induces impairment of endothelial cells function and inhibits angiogenesis.

Porcù E, Viola G, Bortolozzi R, Persano L, Mitola S, Ronca R, Presta M, Romagnoli R, Baraldi PG, Basso G. Porcù E, et al. Angiogenesis. 2013 Jul;16(3):647-62. doi: 10.1007/s10456-013-9343-z. Epub 2013 Mar 2. Angiogenesis. 2013. PMID: 23456551 Free article.

4

Synthesis and biological evaluation of imidazo[1,2-a]pyrimidines and imidazo[1,2-a]pyridines as new inhibitors of the Wnt/β-catenin signaling.

Cosimelli B, Laneri S, Ostacolo C, Sacchi A, Severi E, Porcù E, Rampazzo E, Moro E, Basso G, Viola G. Cosimelli B, et al. Among authors: porcu e. Eur J Med Chem. 2014 Aug 18;83:45-56. doi: 10.1016/j.ejmech.2014.05.071. Epub 2014 Jun 6. Eur J Med Chem. 2014. PMID: 24950489

5

A novel copper(I) complex induces ER-stress-mediated apoptosis and sensitizes B-acute lymphoblastic leukemia cells to chemotherapeutic agents.

Bortolozzi R, Viola G, Porcù E, Consolaro F, Marzano C, Pellei M, Gandin V, Basso G. Bortolozzi R, et al. Among authors: porcu e. Oncotarget. 2014 Aug 15;5(15):5978-91. doi: 10.18632/oncotarget.2027. Oncotarget. 2014. PMID: 24980813 Free PMC article.

6

Recent advances in vascular disrupting agents in cancer therapy.

Porcù E, Bortolozzi R, Basso G, Viola G. Porcù E, et al. Future Med Chem. 2014 Sep;6(13):1485-98. doi: 10.4155/fmc.14.104. Future Med Chem. 2014. PMID: 25365233 Review.

7

Design, synthesis, in vitro, and in vivo anticancer and antiangiogenic activity of novel 3-arylaminobenzofuran derivatives targeting the colchicine site on tubulin.

Romagnoli R, Baraldi PG, Salvador MK, Prencipe F, Lopez-Cara C, Schiaffino Ortega S, Brancale A, Hamel E, Castagliuolo I, Mitola S, Ronca R, Bortolozzi R, Porcù E, Basso G, Viola G. Romagnoli R, et al. Among authors: porcu e. J Med Chem. 2015 Apr 9;58(7):3209-22. doi: 10.1021/acs.jmedchem.5b00155. Epub 2015 Mar 26. J Med Chem. 2015. PMID: 25785605 Free PMC article.

8

Vascular disrupting activity of combretastatin analogues.

Porcù E, Salvador A, Primac I, Mitola S, Ronca R, Ravelli C, Bortolozzi R, Vedaldi D, Romagnoli R, Basso G, Viola G. Porcù E, et al. Vascul Pharmacol. 2016 Aug;83:78-89. doi: 10.1016/j.vph.2016.05.006. Epub 2016 May 25. Vascul Pharmacol. 2016. PMID: 27235861

9

The Novel Antitubulin Agent TR-764 Strongly Reduces Tumor Vasculature and Inhibits HIF-1α Activation.

Porcù E, Persano L, Ronca R, Mitola S, Bortolozzi R, Romagnoli R, Oliva P, Basso G, Viola G. Porcù E, et al. Sci Rep. 2016 Jun 13;6:27886. doi: 10.1038/srep27886. Sci Rep. 2016. PMID: 27292568 Free PMC article.

10

Annexin 2A sustains glioblastoma cell dissemination and proliferation.

Maule F, Bresolin S, Rampazzo E, Boso D, Della Puppa A, Esposito G, Porcù E, Mitola S, Lombardi G, Accordi B, Tumino M, Basso G, Persano L. Maule F, et al. Among authors: porcu e. Oncotarget. 2016 Aug 23;7(34):54632-54649. doi: 10.18632/oncotarget.10565. Oncotarget. 2016. PMID: 27429043 Free PMC article.

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