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Page 1
Characterization of SARS-CoV-2 Spike mutations important for infection of mice and escape from human immune sera.
Rathnasinghe R, Jangra S, Ye C, Cupic A, Singh G, Martínez-Romero C, Mulder LCF, Kehrer T, Yildiz S, Choi A, Yeung ST, Mena I, Gillespie V, De Vrieze J, Aslam S, Stadlbauer D, Meekins DA, McDowell CD, Balaraman V, Corley MJ, Richt JA, De Geest BG, Miorin L; PVI study group; Krammer F, Martinez-Sobrido L, Simon V, García-Sastre A, Schotsaert M. Rathnasinghe R, et al. Among authors: meekins da. Nat Commun. 2022 Jul 7;13(1):3921. doi: 10.1038/s41467-022-30763-0. Nat Commun. 2022. PMID: 35798721 Free PMC article.
Evaluation of A Baculovirus-Expressed VP2 Subunit Vaccine for the Protection of White-Tailed Deer (Odocoileus virginianus) from Epizootic Hemorrhagic Disease.
Sunwoo SY, Noronha LE, Morozov I, Trujillo JD, Kim IJ, Schirtzinger EE, Faburay B, Drolet BS, Urbaniak K, McVey DS, Meekins DA, Palmer MV, Balaraman V, Wilson WC, Richt JA. Sunwoo SY, et al. Among authors: meekins da. Vaccines (Basel). 2020 Jan 31;8(1):59. doi: 10.3390/vaccines8010059. Vaccines (Basel). 2020. PMID: 32023812 Free PMC article.
Susceptibility of swine cells and domestic pigs to SARS-CoV-2.
Meekins DA, Morozov I, Trujillo JD, Gaudreault NN, Bold D, Artiaga BL, Indran SV, Kwon T, Balaraman V, Madden DW, Feldmann H, Henningson J, Ma W, Balasuriya UBR, Richt JA. Meekins DA, et al. bioRxiv [Preprint]. 2020 Aug 16:2020.08.15.252395. doi: 10.1101/2020.08.15.252395. bioRxiv. 2020. Update in: Emerg Microbes Infect. 2020 Dec;9(1):2278-2288. doi: 10.1080/22221751.2020.1831405 PMID: 32817946 Free PMC article. Updated. Preprint.
Susceptibility of swine cells and domestic pigs to SARS-CoV-2.
Meekins DA, Morozov I, Trujillo JD, Gaudreault NN, Bold D, Carossino M, Artiaga BL, Indran SV, Kwon T, Balaraman V, Madden DW, Feldmann H, Henningson J, Ma W, Balasuriya UBR, Richt JA. Meekins DA, et al. Emerg Microbes Infect. 2020 Dec;9(1):2278-2288. doi: 10.1080/22221751.2020.1831405. Emerg Microbes Infect. 2020. PMID: 33003988 Free PMC article.
SARS-CoV-2 infection, disease and transmission in domestic cats.
Gaudreault NN, Trujillo JD, Carossino M, Meekins DA, Morozov I, Madden DW, Indran SV, Bold D, Balaraman V, Kwon T, Artiaga BL, Cool K, García-Sastre A, Ma W, Wilson WC, Henningson J, Balasuriya UBR, Richt JA. Gaudreault NN, et al. Among authors: meekins da. Emerg Microbes Infect. 2020 Dec;9(1):2322-2332. doi: 10.1080/22221751.2020.1833687. Emerg Microbes Infect. 2020. PMID: 33028154 Free PMC article.
Topoisomerase 1 inhibition therapy protects against SARS-CoV-2-induced inflammation and death in animal models.
Yuin Ho JS, Wing-Yee Mok B, Campisi L, Jordan T, Yildiz S, Parameswaran S, Wayman JA, Gaudreault NN, Meekins DA, Indran SV, Morozov I, Trujillo JD, Fstkchyan YS, Rathnasinghe R, Zhu Z, Zheng S, Zhao N, White K, Ray-Jones H, Malysheva V, Thiecke MJ, Lau SY, Liu H, Junxia Zhang A, Chak-Yiu Lee A, Liu WC, Aydillo T, Salom Melo B, Guccione E, Sebra R, Shum E, Bakker J, Kaufman DA, Moreira AL, Carossino M, Balasuriya UBR, Byun M, Miraldi ER, Albrecht RA, Schotsaert M, Garcia-Sastre A, Chanda SK, Jeyasekharan AD, TenOever BR, Spivakov M, Weirauch MT, Heinz S, Chen H, Benner C, Richt JA, Marazzi I. Yuin Ho JS, et al. Among authors: meekins da. bioRxiv [Preprint]. 2020 Dec 1:2020.12.01.404483. doi: 10.1101/2020.12.01.404483. bioRxiv. 2020. Update in: Cell. 2021 May 13;184(10):2618-2632.e17. doi: 10.1016/j.cell.2021.03.051 PMID: 33299999 Free PMC article. Updated. Preprint.
The N501Y mutation in SARS-CoV-2 spike leads to morbidity in obese and aged mice and is neutralized by convalescent and post-vaccination human sera.
Rathnasinghe R, Jangra S, Cupic A, Martínez-Romero C, Mulder LCF, Kehrer T, Yildiz S, Choi A, Mena I, De Vrieze J, Aslam S, Stadlbauer D, Meekins DA, McDowell CD, Balaraman V, Richt JA, De Geest BG, Miorin L; PVI study group; Krammer F, Simon V, García-Sastre A, Schotsaert M. Rathnasinghe R, et al. Among authors: meekins da. medRxiv [Preprint]. 2021 Jan 20:2021.01.19.21249592. doi: 10.1101/2021.01.19.21249592. medRxiv. 2021. PMID: 33501468 Free PMC article. Preprint.
Experimental re-infected cats do not transmit SARS-CoV-2.
Gaudreault NN, Carossino M, Morozov I, Trujillo JD, Meekins DA, Madden DW, Cool K, Artiaga BL, McDowell C, Bold D, Balaraman V, Kwon T, Ma W, Henningson J, Wilson DW, Wilson WC, Balasuriya UBR, García-Sastre A, Richt JA. Gaudreault NN, et al. Among authors: meekins da. Emerg Microbes Infect. 2021 Dec;10(1):638-650. doi: 10.1080/22221751.2021.1902753. Emerg Microbes Infect. 2021. PMID: 33704016 Free PMC article.
TOP1 inhibition therapy protects against SARS-CoV-2-induced lethal inflammation.
Ho JSY, Mok BW, Campisi L, Jordan T, Yildiz S, Parameswaran S, Wayman JA, Gaudreault NN, Meekins DA, Indran SV, Morozov I, Trujillo JD, Fstkchyan YS, Rathnasinghe R, Zhu Z, Zheng S, Zhao N, White K, Ray-Jones H, Malysheva V, Thiecke MJ, Lau SY, Liu H, Zhang AJ, Lee AC, Liu WC, Jangra S, Escalera A, Aydillo T, Melo BS, Guccione E, Sebra R, Shum E, Bakker J, Kaufman DA, Moreira AL, Carossino M, Balasuriya UBR, Byun M, Albrecht RA, Schotsaert M, Garcia-Sastre A, Chanda SK, Miraldi ER, Jeyasekharan AD, TenOever BR, Spivakov M, Weirauch MT, Heinz S, Chen H, Benner C, Richt JA, Marazzi I. Ho JSY, et al. Among authors: meekins da. Cell. 2021 May 13;184(10):2618-2632.e17. doi: 10.1016/j.cell.2021.03.051. Epub 2021 Mar 30. Cell. 2021. PMID: 33836156 Free PMC article.
47 results