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STAT3 in tumor fibroblasts promotes an immunosuppressive microenvironment in pancreatic cancer.
Lefler JE, MarElia-Bennett CB, Thies KA, Hildreth BE 3rd, Sharma SM, Pitarresi JR, Han L, Everett C, Koivisto C, Cuitino MC, Timmers CD, O'Quinn E, Parrish M, Romeo MJ, Linke AJ, Hobbs GA, Leone G, Guttridge DC, Zimmers TA, Lesinski GB, Ostrowski MC. Lefler JE, et al. Among authors: zimmers ta. Life Sci Alliance. 2022 Jul 8;5(11):e202201460. doi: 10.26508/lsa.202201460. Print 2022 Nov. Life Sci Alliance. 2022. PMID: 35803738 Free PMC article.
IL-6 and PD-L1 antibody blockade combination therapy reduces tumour progression in murine models of pancreatic cancer.
Mace TA, Shakya R, Pitarresi JR, Swanson B, McQuinn CW, Loftus S, Nordquist E, Cruz-Monserrate Z, Yu L, Young G, Zhong X, Zimmers TA, Ostrowski MC, Ludwig T, Bloomston M, Bekaii-Saab T, Lesinski GB. Mace TA, et al. Among authors: zimmers ta. Gut. 2018 Feb;67(2):320-332. doi: 10.1136/gutjnl-2016-311585. Epub 2016 Oct 21. Gut. 2018. PMID: 27797936 Free PMC article.
Circulating monocyte chemoattractant protein-1 (MCP-1) is associated with cachexia in treatment-naïve pancreatic cancer patients.
Talbert EE, Lewis HL, Farren MR, Ramsey ML, Chakedis JM, Rajasekera P, Haverick E, Sarna A, Bloomston M, Pawlik TM, Zimmers TA, Lesinski GB, Hart PA, Dillhoff ME, Schmidt CR, Guttridge DC. Talbert EE, et al. Among authors: zimmers ta. J Cachexia Sarcopenia Muscle. 2018 Apr;9(2):358-368. doi: 10.1002/jcsm.12251. Epub 2018 Jan 7. J Cachexia Sarcopenia Muscle. 2018. PMID: 29316343 Free PMC article.
The systemic activin response to pancreatic cancer: implications for effective cancer cachexia therapy.
Zhong X, Pons M, Poirier C, Jiang Y, Liu J, Sandusky GE, Shahda S, Nakeeb A, Schmidt CM, House MG, Ceppa EP, Zyromski NJ, Liu Y, Jiang G, Couch ME, Koniaris LG, Zimmers TA. Zhong X, et al. Among authors: zimmers ta. J Cachexia Sarcopenia Muscle. 2019 Oct;10(5):1083-1101. doi: 10.1002/jcsm.12461. Epub 2019 Jul 8. J Cachexia Sarcopenia Muscle. 2019. PMID: 31286691 Free PMC article.
Combined inhibition of Ref-1 and STAT3 leads to synergistic tumour inhibition in multiple cancers using 3D and in vivo tumour co-culture models.
Caston RA, Shah F, Starcher CL, Wireman R, Babb O, Grimard M, McGeown J, Armstrong L, Tong Y, Pili R, Rupert J, Zimmers TA, Elmi AN, Pollok KE, Motea EA, Kelley MR, Fishel ML. Caston RA, et al. Among authors: zimmers ta. J Cell Mol Med. 2021 Jan;25(2):784-800. doi: 10.1111/jcmm.16132. Epub 2020 Dec 3. J Cell Mol Med. 2021. PMID: 33274592 Free PMC article.
Editorial: Highlights from the 2020 virtual cancer cachexia conference.
Fallon M, Gallouzi IE, Guttridge DC, Zimmers TA. Fallon M, et al. Among authors: zimmers ta. Curr Opin Support Palliat Care. 2021 Mar 1;15(1):48-49. doi: 10.1097/SPC.0000000000000540. Curr Opin Support Palliat Care. 2021. PMID: 33470683 No abstract available.
Cancer cachexia: involvement of an expanding macroenvironment.
Pryce BR, Wang DJ, Zimmers TA, Ostrowski MC, Guttridge DC. Pryce BR, et al. Among authors: zimmers ta. Cancer Cell. 2023 Mar 13;41(3):581-584. doi: 10.1016/j.ccell.2023.02.007. Epub 2023 Mar 2. Cancer Cell. 2023. PMID: 36868225 Free PMC article.
The impact of inflammation and acute phase activation in cancer cachexia.
Robinson TP, Hamidi T, Counts B, Guttridge DC, Ostrowski MC, Zimmers TA, Koniaris LG. Robinson TP, et al. Among authors: zimmers ta. Front Immunol. 2023 Oct 31;14:1207746. doi: 10.3389/fimmu.2023.1207746. eCollection 2023. Front Immunol. 2023. PMID: 38022578 Free PMC article. Review.
124 results