Handin N - Search Results

1

Hepatic Expression of the Na⁺-Taurocholate Cotransporting Polypeptide Is Independent from Genetic Variation.

Tremmel R, Nies AT, van Eijck BAC, Handin N, Haag M, Winter S, Büttner FA, Kölz C, Klein F, Mazzola P, Hofmann U, Klein K, Hoffmann P, Nöthen MM, Gaugaz FZ, Artursson P, Schwab M, Schaeffeler E. Tremmel R, et al. Among authors: handin n. Int J Mol Sci. 2022 Jul 5;23(13):7468. doi: 10.3390/ijms23137468. Int J Mol Sci. 2022. PMID: 35806468 Free PMC article.

2

A CRISPR-Cas9 Generated MDCK Cell Line Expressing Human MDR1 Without Endogenous Canine MDR1 (cABCB1): An Improved Tool for Drug Efflux Studies.

Karlgren M, Simoff I, Backlund M, Wegler C, Keiser M, Handin N, Müller J, Lundquist P, Jareborg AC, Oswald S, Artursson P. Karlgren M, et al. Among authors: handin n. J Pharm Sci. 2017 Sep;106(9):2909-2913. doi: 10.1016/j.xphs.2017.04.018. Epub 2017 Apr 24. J Pharm Sci. 2017. PMID: 28450237

3

A simple approach for restoration of differentiation and function in cryopreserved human hepatocytes.

Ölander M, Wiśniewski JR, Flörkemeier I, Handin N, Urdzik J, Artursson P. Ölander M, et al. Among authors: handin n. Arch Toxicol. 2019 Mar;93(3):819-829. doi: 10.1007/s00204-018-2375-9. Epub 2018 Dec 17. Arch Toxicol. 2019. PMID: 30560367

4

Image-Based Quantification of Cell Debris as a Measure of Apoptosis.

Ölander M, Handin N, Artursson P. Ölander M, et al. Among authors: handin n. Anal Chem. 2019 May 7;91(9):5548-5552. doi: 10.1021/acs.analchem.9b01243. Epub 2019 Apr 25. Anal Chem. 2019. PMID: 31001971 Free article.

5

Common and mutation specific phenotypes of KRAS and BRAF mutations in colorectal cancer cells revealed by integrative -omics analysis.

Kundu S, Ali MA, Handin N, Conway LP, Rendo V, Artursson P, He L, Globisch D, Sjöblom T. Kundu S, et al. Among authors: handin n. J Exp Clin Cancer Res. 2021 Jul 7;40(1):225. doi: 10.1186/s13046-021-02025-2. J Exp Clin Cancer Res. 2021. PMID: 34233735 Free PMC article.

6

High Throughput Screening of a Prescription Drug Library for Inhibitors of Organic Cation Transporter 3, OCT3.

Chen EC, Matsson P, Azimi M, Zhou X, Handin N, Yee SW, Artursson P, Giacomini KM. Chen EC, et al. Among authors: handin n. Pharm Res. 2022 Jul;39(7):1599-1613. doi: 10.1007/s11095-022-03171-8. Epub 2022 Jan 28. Pharm Res. 2022. PMID: 35089508 Free PMC article.

7

The impact of inflammation on the expression of drug transporters and metabolic enzymes in colonic tissue from ulcerative colitis patients.

de Waal T, Handin N, Brouwers J, Ferrante M, Vermeire S, Vanuytsel T, Artursson P, Augustijns P. de Waal T, et al. Among authors: handin n. Int J Pharm. 2022 Nov 25;628:122282. doi: 10.1016/j.ijpharm.2022.122282. Epub 2022 Oct 13. Int J Pharm. 2022. PMID: 36244560

8

Proteome deconvolution of liver biopsies reveals hepatic cell composition as an important marker of fibrosis.

Handin N, Yuan D, Ölander M, Wegler C, Karlsson C, Jansson-Löfmark R, Hjelmesæth J, Åsberg A, Lauschke VM, Artursson P. Handin N, et al. Comput Struct Biotechnol J. 2023 Sep 4;21:4361-4369. doi: 10.1016/j.csbj.2023.08.037. eCollection 2023. Comput Struct Biotechnol J. 2023. PMID: 37711184 Free PMC article.

9

Linking FOXO3, NCOA3, and TCF7L2 to Ras pathway phenotypes through a genome-wide forward genetic screen in human colorectal cancer cells.

Kundu S, Ali MA, Handin N, Padhan N, Larsson J, Karoutsou M, Ban K, Wiśniewski JR, Artursson P, He L, Hellström M, Sjöblom T. Kundu S, et al. Among authors: handin n. Genome Med. 2018 Jan 4;10(1):2. doi: 10.1186/s13073-017-0511-4. Genome Med. 2018. PMID: 29301589 Free PMC article.

10

Hepatocyte size fractionation allows dissection of human liver zonation.

Ölander M, Wegler C, Flörkemeier I, Treyer A, Handin N, Pedersen JM, Vildhede A, Mateus A, LeCluyse EL, Urdzik J, Artursson P. Ölander M, et al. Among authors: handin n. J Cell Physiol. 2021 Aug;236(8):5885-5894. doi: 10.1002/jcp.30273. Epub 2021 Jan 16. J Cell Physiol. 2021. PMID: 33452735

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